|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse ANPEP ORF mammalian expression plasmid, C-GFPSpark tag||MG50001-ACG|
|Mouse ANPEP ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50001-ACR|
|Mouse ANPEP ORF mammalian expression plasmid, C-Flag tag||MG50001-CF|
|Mouse ANPEP ORF mammalian expression plasmid, C-His tag||MG50001-CH|
|Mouse ANPEP ORF mammalian expression plasmid, C-Myc tag||MG50001-CM|
|Mouse ANPEP ORF mammalian expression plasmid, C-HA tag||MG50001-CY|
|Mouse ANPEP Gene cDNA clone plasmid||MG50001-M|
|Mouse ANPEP ORF mammalian expression plasmid, N-Flag tag||MG50001-NF|
|Mouse ANPEP ORF mammalian expression plasmid, N-His tag||MG50001-NH|
|Mouse ANPEP ORF mammalian expression plasmid, N-Myc tag||MG50001-NM|
|Mouse ANPEP ORF mammalian expression plasmid, N-HA tag||MG50001-NY|
|Mouse ANPEP natural ORF mammalian expression plasmid||MG50001-UT|
|Learn more about expression Vectors|
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 family. CD13 plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases and is involved in the metabolism of regulatory peptides by diverse cell types. CD13/APN is a potent regulator of angiogenesis which is essential for tumor invasion and metastasis, and its transcription in activated endothelial cells is induced by angiogenic growth factors via the RAS/MAPK pathway. In addition, this enzyme has been shown to participate in antigen processing and presentation, and accordingly, defects in this gene appear to be a cause of various types of leukemia or lymphoma and carcinomas.