|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CHI3L1 ORF mammalian expression plasmid, C-GFPSpark tag||MG50929-ACG|
|Mouse CHI3L1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50929-ACR|
|Mouse CHI3L1 ORF mammalian expression plasmid, C-Flag tag||MG50929-CF|
|Mouse CHI3L1 ORF mammalian expression plasmid, C-His tag||MG50929-CH|
|Mouse CHI3L1 ORF mammalian expression plasmid, C-Myc tag||MG50929-CM|
|Mouse CHI3L1 ORF mammalian expression plasmid, C-HA tag||MG50929-CY|
|Mouse CHI3L1 Gene cDNA clone plasmid||MG50929-G|
|Mouse CHI3L1 ORF mammalian expression plasmid, N-Flag tag||MG50929-NF|
|Mouse CHI3L1 ORF mammalian expression plasmid, N-His tag||MG50929-NH|
|Mouse CHI3L1 ORF mammalian expression plasmid, N-Myc tag||MG50929-NM|
|Mouse CHI3L1 ORF mammalian expression plasmid, N-HA tag||MG50929-NY|
|Mouse CHI3L1 natural ORF mammalian expression plasmid||MG50929-UT|
|Learn more about expression Vectors|
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.