|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse FOLR2 ORF mammalian expression plasmid, C-GFPSpark tag||MG50927-ACG|
|Mouse FOLR2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50927-ACR|
|Mouse FOLR2 ORF mammalian expression plasmid, C-Flag tag||MG50927-CF|
|Mouse FOLR2 ORF mammalian expression plasmid, C-His tag||MG50927-CH|
|Mouse FOLR2 ORF mammalian expression plasmid, C-Myc tag||MG50927-CM|
|Mouse FOLR2 ORF mammalian expression plasmid, C-HA tag||MG50927-CY|
|Mouse FOLR2 Gene cDNA clone plasmid||MG50927-G|
|Mouse FOLR2 ORF mammalian expression plasmid, N-Flag tag||MG50927-NF|
|Mouse FOLR2 ORF mammalian expression plasmid, N-His tag||MG50927-NH|
|Mouse FOLR2 ORF mammalian expression plasmid, N-Myc tag||MG50927-NM|
|Mouse FOLR2 ORF mammalian expression plasmid, N-HA tag||MG50927-NY|
|Mouse FOLR2 natural ORF mammalian expression plasmid||MG50927-UT|
|Learn more about expression Vectors|
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potocytosis. FOLR2 has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. The FOLR2 protein was originally thought to exist only in placenta, but is also detected in spleen, bone marrow, and thymus. FOLR2 is a marker for macrophages generated in the presence of M-CSF, but not GM-CSF. Its expression correlates with increased folate uptake ability. Folate conjugates of therapeutic drugs are a potential immunotherapy tool to target tumor-associated macrophages.