|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse TACSTD2 ORF mammalian expression plasmid, C-GFPSpark tag||MG50922-ACG|
|Mouse TACSTD2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50922-ACR|
|Mouse TACSTD2 ORF mammalian expression plasmid, C-Flag tag||MG50922-CF|
|Mouse TACSTD2 ORF mammalian expression plasmid, C-His tag||MG50922-CH|
|Mouse TACSTD2 ORF mammalian expression plasmid, C-Myc tag||MG50922-CM|
|Mouse TACSTD2 ORF mammalian expression plasmid, C-HA tag||MG50922-CY|
|Mouse TACSTD2 Gene cDNA clone plasmid||MG50922-G|
|Mouse TACSTD2 ORF mammalian expression plasmid, N-Flag tag||MG50922-NF|
|Mouse TACSTD2 ORF mammalian expression plasmid, N-His tag||MG50922-NH|
|Mouse TACSTD2 ORF mammalian expression plasmid, N-Myc tag||MG50922-NM|
|Mouse TACSTD2 ORF mammalian expression plasmid, N-HA tag||MG50922-NY|
|Mouse TACSTD2 natural ORF mammalian expression plasmid||MG50922-UT|
|Learn more about expression Vectors|
TROP-2, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.