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Human IL17RC Protein (aa 1-454, His Tag)

DatasheetSpecific ReferencesReviewsRelated ProductsProtocols
IL17RCProtein Product Information
Synonym:UNQ6118, PRO20040, PRO38901, FLJ95963, FLJ96005, IL17-RL, IL17RL, MGC10763
Protein Construction:A DNA sequence encoding the full length of human IL17RC isoform 3 (NP_116121.2) (Met 1-Ala 454) was fused with a polyhistidine tag at the carboxy-terminus.
Species:Human
Expressed Host:Baculovirus-Insect Cells
Form & Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
IL17RCProtein QC Testing
Purity:> 90 % as determined by SDS-PAGE
Bio-Activity:1. Measured by its ability to bind with recombinant human IL17A-His (Cat:12047-H07B) in a functional ELISA.
2. Measured by its ability to bind with recombinant human 17A (Cat:12047-HNAE) in a functional ELISA.
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Leu 21
Molecule Mass:The recombinant human IL17RC (aa 1-454) consists of 444 amino acids and predicts a molecular mass of 49.6 kDa. The apparent molecular mass of the protein is approximately 60 kDa in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
IL17RCProtein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
11747-H08B
References
  • Allen W, et al. (2010) IL-17RC: A partner in IL-17 signaling and beyond. Semin Immunopathol. 32(1): 33-42.
  • You ZB, et al. (2007) Differential Expression of IL-17RC Isoforms in Androgen-Dependent and Androgen-Independent Prostate Cancers1. Neoplasia. 9(6): 464-70.
  • Zrioual S, et al. (2008) IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood. J Immunol. 180(1): 655-63.
  • Kuestner RE, et al. (2010) Identification of the IL-17 Receptor Related Molecule IL-17RC as the Receptor for IL-17F. J Immunol.179(8): 5462-73.
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    Size / Price
    Catalog:11747-H08B-50
    List Price: $178.00  (Save $0.00)
    Price:$178.00      [How to order]
    Availabilityon Sale
    Images
    • Human IL17RC Protein (aa 1-454, His Tag) SDS-PAGE
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