|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse EPHA1 ORF mammalian expression plasmid, C-GFPSpark tag||MG50827-ACG|
|Mouse EPHA1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50827-ACR|
|Mouse EPHA1 ORF mammalian expression plasmid, C-Flag tag||MG50827-CF|
|Mouse EPHA1 ORF mammalian expression plasmid, C-His tag||MG50827-CH|
|Mouse EPHA1 ORF mammalian expression plasmid, C-Myc tag||MG50827-CM|
|Mouse EPHA1 ORF mammalian expression plasmid, C-HA tag||MG50827-CY|
|Mouse EPHA1 Gene cDNA clone plasmid||MG50827-G|
|Mouse EPHA1 ORF mammalian expression plasmid, N-Flag tag||MG50827-NF|
|Mouse EPHA1 ORF mammalian expression plasmid, N-His tag||MG50827-NH|
|Mouse EPHA1 ORF mammalian expression plasmid, N-Myc tag||MG50827-NM|
|Mouse EPHA1 ORF mammalian expression plasmid, N-HA tag||MG50827-NY|
|Mouse EPHA1 natural ORF mammalian expression plasmid||MG50827-UT|
|Learn more about expression Vectors|
EPHA1 or EPH receptor A1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. An important role of Eph receptors and their ligands ephrins is to mediate cell-contact-dependent repulsion. Eph receptors and ephrins also act at boundaries to channel neuronal growth cones along specific pathways, restrict the migration of neural crest cells, and via bidirectional signaling prevent intermingling between hindbrain segments. Eph receptors and ephrins can also trigger an adhesive response of endothelial cells and are required for the remodeling of blood vessels. Eph receptors and ephrins have emerged as key regulators of the repulsion and adhesion of cells that underlie the establishment, maintainence, and remodeling of patterns of cellular organization. The ephrins and Eph receptors are implicated as positional labels that may guide the development of neural topographic maps.