|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CD93 ORF mammalian expression plasmid, C-GFPSpark tag||MG50759-ACG|
|Mouse CD93 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50759-ACR|
|Mouse CD93 ORF mammalian expression plasmid, C-Flag tag||MG50759-CF|
|Mouse CD93 ORF mammalian expression plasmid, C-His tag||MG50759-CH|
|Mouse CD93 ORF mammalian expression plasmid, C-Myc tag||MG50759-CM|
|Mouse CD93 ORF mammalian expression plasmid, C-HA tag||MG50759-CY|
|Mouse CD93 Gene cDNA clone plasmid||MG50759-G|
|Mouse CD93 ORF mammalian expression plasmid, N-Flag tag||MG50759-NF|
|Mouse CD93 ORF mammalian expression plasmid, N-His tag||MG50759-NH|
|Mouse CD93 ORF mammalian expression plasmid, N-Myc tag||MG50759-NM|
|Mouse CD93 ORF mammalian expression plasmid, N-HA tag||MG50759-NY|
|Mouse CD93 natural ORF mammalian expression plasmid||MG50759-UT|
|Learn more about expression Vectors|
CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.