|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human ENTPD1 ORF mammalian expression plasmid, C-GFPSpark tag||HG16020-ACG|
|Human ENTPD1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG16020-ACR|
|Human ENTPD1 ORF mammalian expression plasmid, C-Flag tag||HG16020-CF|
|Human ENTPD1 ORF mammalian expression plasmid, C-His tag||HG16020-CH|
|Human ENTPD1 ORF mammalian expression plasmid, C-Myc tag||HG16020-CM|
|Human ENTPD1 ORF mammalian expression plasmid, C-HA tag||HG16020-CY|
|Human ENTPD1 Gene cDNA clone plasmid||HG16020-G|
|Human ENTPD1 ORF mammalian expression plasmid, N-Flag tag||HG16020-NF|
|Human ENTPD1 ORF mammalian expression plasmid, N-His tag||HG16020-NH|
|Human ENTPD1 ORF mammalian expression plasmid, N-Myc tag||HG16020-NM|
|Human ENTPD1 ORF mammalian expression plasmid, N-HA tag||HG16020-NY|
|Human ENTPD1 natural ORF mammalian expression plasmid||HG16020-UT|
|Learn more about expression Vectors|
CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism. There is a correlation between ATP hydrolysis and triglycerides in patients with chronic heart disease, suggesting a relationship between ATP diphosphohydrolase and thrombogenesis. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.