|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse SDC4 ORF mammalian expression plasmid, C-GFPSpark tag||MG50726-ACG|
|Mouse SDC4 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50726-ACR|
|Mouse SDC4 ORF mammalian expression plasmid, C-Flag tag||MG50726-CF|
|Mouse SDC4 ORF mammalian expression plasmid, C-His tag||MG50726-CH|
|Mouse SDC4 ORF mammalian expression plasmid, C-Myc tag||MG50726-CM|
|Mouse SDC4 ORF mammalian expression plasmid, C-HA tag||MG50726-CY|
|Mouse SDC4 Gene cDNA clone plasmid||MG50726-G|
|Mouse SDC4 ORF mammalian expression plasmid, N-Flag tag||MG50726-NF|
|Mouse SDC4 ORF mammalian expression plasmid, N-His tag||MG50726-NH|
|Mouse SDC4 ORF mammalian expression plasmid, N-Myc tag||MG50726-NM|
|Mouse SDC4 ORF mammalian expression plasmid, N-HA tag||MG50726-NY|
|Mouse SDC4 natural ORF mammalian expression plasmid||MG50726-UT|
|Learn more about expression Vectors|
SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with a number of signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty.