|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CD24A ORF mammalian expression plasmid, C-GFPSpark tag||MG50717-ACG|
|Mouse CD24A ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50717-ACR|
|Mouse CD24A ORF mammalian expression plasmid, C-Flag tag||MG50717-CF|
|Mouse CD24A ORF mammalian expression plasmid, C-His tag||MG50717-CH|
|Mouse CD24A ORF mammalian expression plasmid, C-Myc tag||MG50717-CM|
|Mouse CD24A ORF mammalian expression plasmid, C-HA tag||MG50717-CY|
|Mouse CD24A Gene cDNA clone plasmid||MG50717-G|
|Mouse CD24A ORF mammalian expression plasmid, N-Flag tag||MG50717-NF|
|Mouse CD24A ORF mammalian expression plasmid, N-His tag||MG50717-NH|
|Mouse CD24A ORF mammalian expression plasmid, N-Myc tag||MG50717-NM|
|Mouse CD24A ORF mammalian expression plasmid, N-HA tag||MG50717-NY|
|Mouse CD24A natural ORF mammalian expression plasmid||MG50717-UT|
|Learn more about expression Vectors|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 24, also known as signal transducer CD24 or heat stable antigen CD24 (HSA), is a mucin-type glycosylphosphatidylinositol-linked glycoprotein expressed on the surface of B-cells, differentiating neuroblasts and many tumors. It is involved in molecular adhesion and metastatic tumor spread and serve as a normal receptor for P-selectin. The CD24 / P-selectin pathway could be important in dissimenating of tumor cells by facilitating the interaction with platelet and endothelial cells. It has also been considered as a tumor marker. High rate of CD24 expressions have been found in epithelial ovarian cancer, breast cancer, non-small cell lung cancer, prostate cancer and pancreatic cancer.