|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CD302 ORF mammalian expression plasmid, C-GFPSpark tag||MG50706-ACG|
|Mouse CD302 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50706-ACR|
|Mouse CD302 ORF mammalian expression plasmid, C-Flag tag||MG50706-CF|
|Mouse CD302 ORF mammalian expression plasmid, C-His tag||MG50706-CH|
|Mouse CD302 ORF mammalian expression plasmid, C-Myc tag||MG50706-CM|
|Mouse CD302 ORF mammalian expression plasmid, C-HA tag||MG50706-CY|
|Mouse CD302 Gene cDNA clone plasmid||MG50706-M|
|Mouse CD302 ORF mammalian expression plasmid, N-Flag tag||MG50706-NF|
|Mouse CD302 ORF mammalian expression plasmid, N-His tag||MG50706-NH|
|Mouse CD302 ORF mammalian expression plasmid, N-Myc tag||MG50706-NM|
|Mouse CD302 ORF mammalian expression plasmid, N-HA tag||MG50706-NY|
|Mouse CD302 natural ORF mammalian expression plasmid||MG50706-UT|
|Learn more about expression Vectors|
CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.