|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse FCER2A ORF mammalian expression plasmid, C-GFPSpark tag||MG50695-ACG|
|Mouse FCER2A ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50695-ACR|
|Mouse FCER2A ORF mammalian expression plasmid, C-Flag tag||MG50695-CF|
|Mouse FCER2A ORF mammalian expression plasmid, C-His tag||MG50695-CH|
|Mouse FCER2A ORF mammalian expression plasmid, C-Myc tag||MG50695-CM|
|Mouse FCER2A ORF mammalian expression plasmid, C-HA tag||MG50695-CY|
|Mouse FCER2A Gene cDNA clone plasmid||MG50695-G|
|Mouse FCER2A ORF mammalian expression plasmid, N-Flag tag||MG50695-NF|
|Mouse FCER2A ORF mammalian expression plasmid, N-His tag||MG50695-NH|
|Mouse FCER2A ORF mammalian expression plasmid, N-Myc tag||MG50695-NM|
|Mouse FCER2A ORF mammalian expression plasmid, N-HA tag||MG50695-NY|
|Mouse FCER2A natural ORF mammalian expression plasmid||MG50695-UT|
|Learn more about expression Vectors|
Fc fragment of IgE, low affinity II, receptor for (CD23) or CD23 antigen is a member of the cluster of differentiation family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD23/FCER2 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Increased levels of soluble CD23/FCER2 cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen-specific B-cells, therefore increasing the production of allergen specific IgE. IgE, in turn, is known to upregulate the cellular expression of CD23 and Fc epsilon RI (high-affinity IgE receptor).