|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse ENPP-7 ORF mammalian expression plasmid, C-GFPSpark tag||MG50567-ACG|
|Mouse ENPP-7 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50567-ACR|
|Mouse ENPP-7 ORF mammalian expression plasmid, C-Flag tag||MG50567-CF|
|Mouse ENPP-7 ORF mammalian expression plasmid, C-His tag||MG50567-CH|
|Mouse ENPP-7 ORF mammalian expression plasmid, C-Myc tag||MG50567-CM|
|Mouse ENPP-7 ORF mammalian expression plasmid, C-HA tag||MG50567-CY|
|Mouse ENPP-7 Gene cDNA clone plasmid||MG50567-M|
|Mouse ENPP-7 ORF mammalian expression plasmid, N-Flag tag||MG50567-NF|
|Mouse ENPP-7 ORF mammalian expression plasmid, N-His tag||MG50567-NH|
|Mouse ENPP-7 ORF mammalian expression plasmid, N-Myc tag||MG50567-NM|
|Mouse ENPP-7 ORF mammalian expression plasmid, N-HA tag||MG50567-NY|
|Mouse ENPP-7 natural ORF mammalian expression plasmid||MG50567-UT|
|Learn more about expression Vectors|
Mouse Ectonucleotide pyrophosphatase / phosphodiesterase family member 7, also known as Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-Smase, ENPP7 and NPP-7, is a single-pass type I membrane protein which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP7 / NPP-7 is expressed in the intestines and human bile. ENPP7 / NPP-7 is localized at the surface of the microvillar membrane in small intestine enterocytes, as well as in endosome-like structures and in Golgi complex. The main function of ENPP7 / NPP-7 is to convert the dietary sphingomyelin into ceramide, the sphingolipid messengers via hydrolyzation. ENPP7 / NPP-7 is also reported to exert a phospholipase C activity toward palmitoyl lyso-phosphocholine. The activity of this enzyme is inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Further, It has been shown in studies that decreased levels of ENPP7 / NPP-7 may be associated with human colon cancer.