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Human FGF6 / FGF-6 Protein

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Human FGF6 Protein Product Information
Synonym:FGF6, HST2 HSTF2
Protein Construction:A DNA sequence encoding the mature form of human FGF6 (Gly41-Ile208) was expressed with a N-terminal Met.
Species:Human
Expressed Host:E. coli
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human FGF6 Protein QC Testing
Purity:> 95 % as determined by SDS-PAGE
Bio-Activity:Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts.
The ED50 for this effect is typically 0.1-0.6 ng/mL.
Endotoxin:Please contact us for more information.
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Met
Molecule Mass:The recombinant human FGF6 consists of 169 amino acids and predicts a molecular mass of 18.9 KDa. It migrates as an approximately 19 KDa band in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human FGF6 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Other FGF6 Recombinant Protein Products
11528-HNAE
FGF6 / FGF-6 Background

FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis. It is also required for normal muscle regeneration. FGF6 gene displayed oncogenic transforming activity when transfected into mammalian cells.

Human FGF6 / FGF-6 References
  • Marics I, et al. (1989) Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family. Oncogene. 4(3):335-40.
  • Coulier F, et al. (1991) Putative structure of the FGF6 gene product and role of the signal peptide. Oncogene. 6(8):1437-44.
  • Iida S, et al. (1992) Human hst-2 (FGF-6) oncogene: cDNA cloning and characterization. Oncogene. 7(2):303-9.
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    Catalog: 11528-HNAE-5
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    • Human FGF6 / FGF-6 Protein SDS-PAGE
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