|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Rat CSF2RB ORF mammalian expression plasmid, C-GFPSpark tag||RG80323-ACG|
|Rat CSF2RB ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80323-ACR|
|Rat CSF2RB ORF mammalian expression plasmid, C-Flag tag||RG80323-CF|
|Rat CSF2RB ORF mammalian expression plasmid, C-His tag||RG80323-CH|
|Rat CSF2RB ORF mammalian expression plasmid, C-Myc tag||RG80323-CM|
|Rat CSF2RB ORF mammalian expression plasmid, C-HA tag||RG80323-CY|
|Rat CSF2RB Gene cDNA clone plasmid||RG80323-G|
|Rat CSF2RB ORF mammalian expression plasmid, N-Flag tag||RG80323-NF|
|Rat CSF2RB ORF mammalian expression plasmid, N-His tag||RG80323-NH|
|Rat CSF2RB ORF mammalian expression plasmid, N-Myc tag||RG80323-NM|
|Rat CSF2RB ORF mammalian expression plasmid, N-HA tag||RG80323-NY|
|Rat CSF2RB natural ORF mammalian expression plasmid||RG80323-UT|
|Learn more about expression Vectors|
Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (IL3RB), is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this protein have been reported to be associated with protein alveolar proteinosis (PAP). CD131 belongs to the type I cytokine receptor family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Defects in CD131/CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5). SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.