|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Mouse FLT3 ORF mammalian expression plasmid, C-GFPSpark tag||MG51119-ACG|
|Mouse FLT3 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG51119-ACR|
|Mouse FLT3 ORF mammalian expression plasmid, C-Flag tag||MG51119-CF|
|Mouse FLT3 ORF mammalian expression plasmid, C-His tag||MG51119-CH|
|Mouse FLT3 ORF mammalian expression plasmid, C-Myc tag||MG51119-CM|
|Mouse FLT3 ORF mammalian expression plasmid, C-HA tag||MG51119-CY|
|Mouse FLT3 Gene cDNA clone plasmid||MG51119-G|
|Mouse FLT3 ORF mammalian expression plasmid, N-Flag tag||MG51119-NF|
|Mouse FLT3 ORF mammalian expression plasmid, N-His tag||MG51119-NH|
|Mouse FLT3 ORF mammalian expression plasmid, N-Myc tag||MG51119-NM|
|Mouse FLT3 ORF mammalian expression plasmid, N-HA tag||MG51119-NY|
|Mouse FLT3 natural ORF mammalian expression plasmid||MG51119-UT|
|Learn more about expression Vectors|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD135, also known as FLT-3, FLK-2, is a member of the CD system. CD135 is an important cell surface marker recognized by specific sets of antibodies to identify the types of hematopoietic (blood) progenitors in the bone marrow and it function to differentiate hematopoietic stem cells, which are CD135 negative, from multipotent progenitors, which are CD135 positive. CD135 is a receptor tyrosine kinase typeⅢ for the cytokine Flt3 ligand and activat signaling through second messengers by binding to Flt3. Signaling through CD135 is important for lymphocyte development. The encoding gene CD135 is a proto-oncogene to which mutations happened will lead to cancer such as leukemia.