|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CST7 ORF mammalian expression plasmid, C-GFPSpark tag||MG50236-ACG|
|Mouse CST7 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50236-ACR|
|Mouse CST7 ORF mammalian expression plasmid, C-Flag tag||MG50236-CF|
|Mouse CST7 ORF mammalian expression plasmid, C-His tag||MG50236-CH|
|Mouse CST7 ORF mammalian expression plasmid, C-Myc tag||MG50236-CM|
|Mouse CST7 ORF mammalian expression plasmid, C-HA tag||MG50236-CY|
|Mouse CST7 Gene cDNA clone plasmid||MG50236-M|
|Mouse CST7 ORF mammalian expression plasmid, N-Flag tag||MG50236-NF|
|Mouse CST7 ORF mammalian expression plasmid, N-His tag||MG50236-NH|
|Mouse CST7 ORF mammalian expression plasmid, N-Myc tag||MG50236-NM|
|Mouse CST7 ORF mammalian expression plasmid, N-HA tag||MG50236-NY|
|Mouse CST7 natural ORF mammalian expression plasmid||MG50236-UT|
|Learn more about expression Vectors|
The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.