|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Rat FIGF ORF mammalian expression plasmid, C-GFPSpark tag||RG80104-ACG|
|Rat FIGF ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80104-ACR|
|Rat FIGF ORF mammalian expression plasmid, C-Flag tag||RG80104-CF|
|Rat FIGF ORF mammalian expression plasmid, C-His tag||RG80104-CH|
|Rat FIGF ORF mammalian expression plasmid, C-Myc tag||RG80104-CM|
|Rat FIGF ORF mammalian expression plasmid, C-HA tag||RG80104-CY|
|Rat FIGF Gene cDNA clone plasmid||RG80104-G|
|Rat FIGF ORF mammalian expression plasmid, N-Flag tag||RG80104-NF|
|Rat FIGF ORF mammalian expression plasmid, N-His tag||RG80104-NH|
|Rat FIGF ORF mammalian expression plasmid, N-Myc tag||RG80104-NM|
|Rat FIGF ORF mammalian expression plasmid, N-HA tag||RG80104-NY|
|Rat FIGF natural ORF mammalian expression plasmid||RG80104-UT|
|Learn more about expression Vectors|
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.