|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CD28 ORF mammalian expression plasmid, C-GFPSpark tag||MG50103-ACG|
|Mouse CD28 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50103-ACR|
|Mouse CD28 ORF mammalian expression plasmid, C-Flag tag||MG50103-CF|
|Mouse CD28 ORF mammalian expression plasmid, C-His tag||MG50103-CH|
|Mouse CD28 ORF mammalian expression plasmid, C-Myc tag||MG50103-CM|
|Mouse CD28 ORF mammalian expression plasmid, C-HA tag||MG50103-CY|
|Mouse CD28 Gene cDNA clone plasmid||MG50103-M|
|Mouse CD28 ORF mammalian expression plasmid, N-Flag tag||MG50103-NF|
|Mouse CD28 ORF mammalian expression plasmid, N-His tag||MG50103-NH|
|Mouse CD28 ORF mammalian expression plasmid, N-Myc tag||MG50103-NM|
|Mouse CD28 ORF mammalian expression plasmid, N-HA tag||MG50103-NY|
|Mouse CD28 natural ORF mammalian expression plasmid||MG50103-UT|
|Learn more about expression Vectors|
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.