|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CCL20 ORF mammalian expression plasmid, C-GFPSpark tag||MG50048-ACG|
|Mouse CCL20 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50048-ACR|
|Mouse CCL20 ORF mammalian expression plasmid, C-Flag tag||MG50048-CF|
|Mouse CCL20 ORF mammalian expression plasmid, C-His tag||MG50048-CH|
|Mouse CCL20 ORF mammalian expression plasmid, C-Myc tag||MG50048-CM|
|Mouse CCL20 ORF mammalian expression plasmid, C-HA tag||MG50048-CY|
|Mouse CCL20 Gene cDNA clone plasmid||MG50048-M|
|Mouse CCL20 ORF mammalian expression plasmid, N-Flag tag||MG50048-NF|
|Mouse CCL20 ORF mammalian expression plasmid, N-His tag||MG50048-NH|
|Mouse CCL20 ORF mammalian expression plasmid, N-Myc tag||MG50048-NM|
|Mouse CCL20 ORF mammalian expression plasmid, N-HA tag||MG50048-NY|
|Mouse CCL20 natural ORF mammalian expression plasmid||MG50048-UT|
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Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products (including LPS, dsRNA, and PMA). MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis.