|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CD5L ORF mammalian expression plasmid, C-GFPSpark tag||MG50020-ACG|
|Mouse CD5L ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50020-ACR|
|Mouse CD5L ORF mammalian expression plasmid, C-Flag tag||MG50020-CF|
|Mouse CD5L ORF mammalian expression plasmid, C-His tag||MG50020-CH|
|Mouse CD5L ORF mammalian expression plasmid, C-Myc tag||MG50020-CM|
|Mouse CD5L ORF mammalian expression plasmid, C-HA tag||MG50020-CY|
|Mouse CD5L Gene cDNA clone plasmid||MG50020-M|
|Mouse CD5L ORF mammalian expression plasmid, N-Flag tag||MG50020-NF|
|Mouse CD5L ORF mammalian expression plasmid, N-His tag||MG50020-NH|
|Mouse CD5L ORF mammalian expression plasmid, N-Myc tag||MG50020-NM|
|Mouse CD5L ORF mammalian expression plasmid, N-HA tag||MG50020-NY|
|Mouse CD5L natural ORF mammalian expression plasmid||MG50020-UT|
|Learn more about expression Vectors|
CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.