|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CAXII ORF mammalian expression plasmid, C-GFPSpark tag||MG50014-ACG|
|Mouse CAXII ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50014-ACR|
|Mouse CAXII ORF mammalian expression plasmid, C-Flag tag||MG50014-CF|
|Mouse CAXII ORF mammalian expression plasmid, C-His tag||MG50014-CH|
|Mouse CAXII ORF mammalian expression plasmid, C-Myc tag||MG50014-CM|
|Mouse CAXII ORF mammalian expression plasmid, C-HA tag||MG50014-CY|
|Mouse CAXII Gene cDNA clone plasmid||MG50014-M|
|Mouse CAXII ORF mammalian expression plasmid, N-Flag tag||MG50014-NF|
|Mouse CAXII ORF mammalian expression plasmid, N-His tag||MG50014-NH|
|Mouse CAXII ORF mammalian expression plasmid, N-Myc tag||MG50014-NM|
|Mouse CAXII ORF mammalian expression plasmid, N-HA tag||MG50014-NY|
|Mouse CAXII natural ORF mammalian expression plasmid||MG50014-UT|
|Learn more about expression Vectors|
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker. rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity.