|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CAXIV ORF mammalian expression plasmid, C-GFPSpark tag||MG50013-ACG|
|Mouse CAXIV ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50013-ACR|
|Mouse CAXIV ORF mammalian expression plasmid, C-Flag tag||MG50013-CF|
|Mouse CAXIV ORF mammalian expression plasmid, C-His tag||MG50013-CH|
|Mouse CAXIV ORF mammalian expression plasmid, C-Myc tag||MG50013-CM|
|Mouse CAXIV ORF mammalian expression plasmid, C-HA tag||MG50013-CY|
|Mouse CAXIV Gene cDNA clone plasmid||MG50013-M|
|Mouse CAXIV ORF mammalian expression plasmid, N-Flag tag||MG50013-NF|
|Mouse CAXIV ORF mammalian expression plasmid, N-His tag||MG50013-NH|
|Mouse CAXIV ORF mammalian expression plasmid, N-Myc tag||MG50013-NM|
|Mouse CAXIV ORF mammalian expression plasmid, N-HA tag||MG50013-NY|
|Mouse CAXIV natural ORF mammalian expression plasmid||MG50013-UT|
|Learn more about expression Vectors|
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. CAXIV is a member of CA family that showed an overall similarity of 29–46% to other active CA isozymes. The highest percentage similarity was with a transmembrane CA isoform, CAXII. The CAXIV was found high concentrations in human heart, brain, liver, and skeletal muscle but lower in the colon, small intestine, urinary bladder, and kidney. No CAXIV mRNA was seen in the salivary gland and pancreas. CAXIV is a likely candidate for the extracellular CA postulated to have an important role in modulating excitatory synaptic transmission in brain.