Quick Order

Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone)

DatasheetSpecific ReferencesReviewsRelated ProductsProtocols
ENSAcDNA Clone Product Information
Gene_bank_ref_id:XM_005541982.1
cDNA Size:366
cDNA Description:ORF Clone of Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) endosulfine alpha DNA.
Gene Synonym:ENSA
Species:Cynomolgus
Vector:pGEM-T Vector
Restriction Site:
Tag Sequence:
Sequence Description:Identical with the Gene Bank Ref. ID sequence except for the point mutation: 62T>C(M21T). Please check the sequence information before order.
Shipping_carrier:Each tube contains approximately 10 μg of lyophilized plasmid.
Storage:The lyophilized plasmid can be stored at ambient temperature for three months.
pGEM-T Vector Information

The pGEM-T is 3kb in length, and contains the amplicin resistance gene, conferring selection of the plasmid in E. coli, and the ori site which is the bacterial origin of replication. The plasmid has multiple cloning sites as shown below. The coding sequence was inserted by TA cloning. Many E. coli strains are suitable for the propagation of this vector including JM109, DH5α and TOP10.

pGEM-T Simple Usage Suggestion:

The coding sequence can be easily obtained by digesting the vector with proper restriction enzyme(s). The coding sequence can also be amplified by PCR with M13 primers, or primer pair SP6 and T7.

Vector Sequence Download
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone) on other vectors
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-taggedCG90656-ACG$325
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tagCG90656-ACR$325
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, N-GFPSpark-taggedCG90656-ANG$325
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, N-OFPSpark tagCG90656-ANR$325
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-taggedCG90656-CF$295
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedCG90656-CH$295
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedCG90656-CM$295
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedCG90656-CY$295
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone)CG90656-G$95
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedCG90656-NF$295
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedCG90656-NH$295
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedCG90656-NM$295
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedCG90656-NY$295
Cynomolgus monkey ENSA Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedCG90656-UT$295
 Learn more about expression Vectors
Related Products
Product nameProduct name
Background

Endosulfine alpha, also known as ENSA, belongs to the endosulfine family. It is a highly conserved cAMP-regulated phosphoprotein (ARPP) family. Endosulfine alpha is widely expressed with high levels in skeletal muscle and brain and lower levels in the pancreas. As a protein phosphatase inhibitor, ENSA specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase By similarity. Endosulfine alpha also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.

References
  • Ye M. et al., 2001, Genome Res. 10 (10): 1546-60.
  • Apiou F. et al., 1999, Diabetes 48 (9): 1873-6.
  • Lennon G. et al., 1997, Genome Res. 6 (9): 791-806.
  • Size / Price
    Catalog:CG90656-G
    List Price: $95.00  (Save $0.00)
    Price:$95.00      [How to order]
    Availability2-3 weeks
    Images
      Recently Viewed Items
        Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"