|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Mouse SCF ORF mammalian expression plasmid, C-GFPSpark tag||MG50487-ACG|
|Mouse SCF ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50487-ACR|
|Mouse SCF ORF mammalian expression plasmid, C-Flag tag||MG50487-CF|
|Mouse SCF ORF mammalian expression plasmid, C-His tag||MG50487-CH|
|Mouse SCF ORF mammalian expression plasmid, C-Myc tag||MG50487-CM|
|Mouse SCF ORF mammalian expression plasmid, C-HA tag||MG50487-CY|
|Mouse SCF Gene cDNA clone plasmid||MG50487-M|
|Mouse SCF ORF mammalian expression plasmid, Flag tag||MG50487-M-F|
|Mouse SCF ORF mammalian expression plasmid, N-Flag tag||MG50487-NF|
|Mouse SCF ORF mammalian expression plasmid, N-His tag||MG50487-NH|
|Mouse SCF ORF mammalian expression plasmid, N-Myc tag||MG50487-NM|
|Mouse SCF ORF mammalian expression plasmid, N-HA tag||MG50487-NY|
|Mouse SCF natural ORF mammalian expression plasmid||MG50487-UT|
|Learn more about expression Vectors|
Similar to Kit ligand precursor (C-kit ligand) , also known as Stem cell factor (SCF), Mast cell growth factor (MGF) or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. SCF/C-kit ligand stimulates the proliferation of mast cells. This protein is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It may act synergistically with other cytokines, probably interleukins SCF/C-kit ligand is the ligand for the tyrosine kinase receptor c-kit, which is expressed on both primitive and mature hematopoietic progenitor cells. In vitro, SCF/C-kit ligand synergizes with other growth factors, such as granulocyte colony-stimulating factor (G-CSF), granulocyte macrophage- colony- stimulating factor, and interleukin-3 to stimulate the proliferation and differentiation of cells of the lymphoid, myeloid, erythroid, and megakaryocytic lineages. In vivo, SCF/C-kit also synergizes with other growth factors and has been shown to enhance the mobilization of peripheral blood progenitor cells in combination with G-CSF. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.