|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human IGFBP1 ORF mammalian expression plasmid, C-GFPSpark tag||HG16132-ACG|
|Human IGFBP1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG16132-ACR|
|Human IGFBP1 ORF mammalian expression plasmid, C-Flag tag||HG16132-CF|
|Human IGFBP1 ORF mammalian expression plasmid, C-His tag||HG16132-CH|
|Human IGFBP1 ORF mammalian expression plasmid, C-Myc tag||HG16132-CM|
|Human IGFBP1 ORF mammalian expression plasmid, C-HA tag||HG16132-CY|
|Human IGFBP1 Gene cDNA clone plasmid||HG16132-G|
|Human IGFBP1 ORF mammalian expression plasmid, N-Flag tag||HG16132-NF|
|Human IGFBP1 ORF mammalian expression plasmid, N-His tag||HG16132-NH|
|Human IGFBP1 ORF mammalian expression plasmid, N-Myc tag||HG16132-NM|
|Human IGFBP1 ORF mammalian expression plasmid, N-HA tag||HG16132-NY|
|Human IGFBP1 natural ORF mammalian expression plasmid||HG16132-UT|
|Learn more about expression Vectors|
IGFBP1, also known as IGFBP-1 and insulin-like growth factor-binding protein 1, is a member of the insulin-like growth factor binding protein family. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology with each other and have binding affinities for IGF-I and IGF-II at the same order of magnitude as the ligands have for the IGF-IR. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP1 has an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.