|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.
|Mouse CD93 ORF mammalian expression plasmid, C-GFPSpark tag||MG50759-ACG|
|Mouse CD93 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50759-ACR|
|Mouse CD93 ORF mammalian expression plasmid, C-Flag tag||MG50759-CF|
|Mouse CD93 ORF mammalian expression plasmid, C-His tag||MG50759-CH|
|Mouse CD93 ORF mammalian expression plasmid, C-Myc tag||MG50759-CM|
|Mouse CD93 ORF mammalian expression plasmid, C-HA tag||MG50759-CY|
|Mouse CD93 Gene cDNA clone plasmid||MG50759-G|
|Mouse CD93 ORF mammalian expression plasmid, N-Flag tag||MG50759-NF|
|Mouse CD93 ORF mammalian expression plasmid, N-His tag||MG50759-NH|
|Mouse CD93 ORF mammalian expression plasmid, N-Myc tag||MG50759-NM|
|Mouse CD93 ORF mammalian expression plasmid, N-HA tag||MG50759-NY|
|Mouse CD93 natural ORF mammalian expression plasmid||MG50759-UT|
|Learn more about expression Vectors|
CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.