|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.
|Mouse EPHB3 ORF mammalian expression plasmid, C-GFPSpark tag||MG50581-ACG|
|Mouse EPHB3 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50581-ACR|
|Mouse EPHB3 ORF mammalian expression plasmid, C-Flag tag||MG50581-CF|
|Mouse EPHB3 ORF mammalian expression plasmid, C-His tag||MG50581-CH|
|Mouse EPHB3 ORF mammalian expression plasmid, C-Myc tag||MG50581-CM|
|Mouse EPHB3 ORF mammalian expression plasmid, C-HA tag||MG50581-CY|
|Mouse EPHB3 Gene cDNA clone plasmid||MG50581-M|
|Mouse EPHB3 ORF mammalian expression plasmid, N-Flag tag||MG50581-NF|
|Mouse EPHB3 ORF mammalian expression plasmid, N-His tag||MG50581-NH|
|Mouse EPHB3 ORF mammalian expression plasmid, N-Myc tag||MG50581-NM|
|Mouse EPHB3 ORF mammalian expression plasmid, N-HA tag||MG50581-NY|
|Mouse EPHB3 natural ORF mammalian expression plasmid||MG50581-UT|
|Learn more about expression Vectors|
Ephrin type-B receptor 3, also known as EphB3 or HEK2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. EphB receptor tyrosine kinases are enriched at synapses, suggesting that these receptors play a role in synapse formation or function. We find that EphrinB binding to EphB induces a direct interaction of EphB with NMDA-type glutamate receptors. This interaction occurs at the cell surface and is mediated by the extracellular regions of the two receptors, but does not require the kinase activity of EphB.