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OMGP Antibody, Rabbit PAb, Antigen Affinity Purified

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Human OMG/OMGP Antibody Product Information
Immunogen:Recombinant Human OMGP protein (Catalog#10269-H08H)
Clone ID:
Ig Type:Rabbit IgG
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human OMGP (rh OMGP; Catalog#10269-H08H; P23515-1; Met 1-Pro 416). OMGP specific IgG was purified by Human OMGP affinity chromatography.
Human OMG/OMGP Antibody Usage Guide
Specificity:Human OMGP
Application:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human OMG / OMGP (aa 1-416). The detection limit for Human OMG / OMGP (aa 1-416) is approximately 0.00975 ng/well.

IHC-P: 0.5-2 μg/mL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human OMG/OMGP Antibody IHC Application Image
[Click to enlarge image]
Immunochemical staining of human OMGP in human stomach with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
OMGP Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Other OMG/OMGP Antibody Products
OMGP Background

Mouse oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein which contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP participats in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR, the receptor for Nogo. This function requires its leucine-rich repeat domain, a highly conserved region in OMgp during mammal evolution. OMG / OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation, neuronal sprouting and myelination are crucial processes involved in brain development and regeneration after injury.

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All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.