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KLK13 / Kallikrein 13 Antibody, Mouse MAb

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KLK-13Antibody Product Information
Immunogen:Recombinant Human KLK13 protein (Catalog#10199-H08H)
Clone ID:10H10A2C4
Ig Type:Mouse IgG2a
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KLK13 / Kallikrein13 (rhKLK13; Catalog#10199-H08H; NP_056411.1; Met 1-Ile 262). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
KLK-13Antibody Usage Guide
Specificity:Human KLK13 / Kallikrein 13
No cross-reactivity with Human cell lysate (293 cell line) in WB and ELISA.
Application:ELISA

ELISA: 0.5-1 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human KLK13. The detection limit for Human KLK13 is approximately 0.3 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Background

Human tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers, and is regarded as a novel cancer biomarker. In addition, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones.

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Catalog:10199-MM01-50
List Price: $135.00  (Save $0.00)
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