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CD31 / PECAM1 Antibody (FITC), Mouse MAb

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Human CD31/PECAM1 Antibody Product Information
Immunogen:Recombinant Human CD31 protein (Catalog#10148-H08H)
Clone ID:02
Ig Type:Mouse IgG1
Concentration:10 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD31 / PECAM1 (rhCD31; Catalog#10148-H08H; Met 1-Lys 601; NP_000433.3) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Human CD31/PECAM1 Antibody Usage Guide
Specificity:Human CD31 / PECAM1
No cross-reactivity in ELISA with
Human CD54
Human CD62
Human CD106
Human cell lysate (293 cell line)
Storage:This antibody is stable for 24 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Human CD31/PECAM1 Antibody FC Application Image
[Click to enlarge image]
Profile of peripheral blood lymphocytes and blood monocytes analyzed by flow cytometry.
CD31 / PECAM1 Antibody (FITC), Mouse MAb, Flow cytometric
Other CD31/PECAM1 Antibody Products
CD31/PECAM-1 Background

The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.

Human CD31/PECAM-1 References
  • Deaglio S, et al. (2000) CD38/CD31, a receptor/ligand system ruling adhesion and signaling in human leukocytes. Chem Immunol. 75: 99-120.
  • Kohler S, et al. (2009) Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets. Blood. 113(4): 769-74.
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