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Human REG1A Gene ORF cDNA clone expression plasmid, N-His tag

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Expression host: Human Cells  
  • Slide 1
11234-H08H-50
11234-H08H-100
50 µg 
100 µg 
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Expression host: Human Cells  
  • Slide 1
80300-R02H-20
80300-R02H-100
20 µg 
100 µg 
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Expression host: Human Cells  
  • Slide 1
90162-C08H-20
90162-C08H-100
20 µg 
100 µg 
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Expression host: Human Cells  
  • Slide 1
90162-C02H-20
90162-C02H-100
20 µg 
100 µg 
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Reactivity: Human  
Application: 
  • Slide 1
11234-MM07-50
11234-MM07-200
11234-MM07-100
50 µg 
200 µg 
100 µg 
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Reactivity: Human  
Application: 
    11234-MM09-50
    11234-MM09-200
    11234-MM09-100
    50 µg 
    200 µg 
    100 µg 
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    Reactivity: Human  
    Application: ELISA  IF  ICC/IF  
    • Slide 1
    11234-MM03-50
    11234-MM03-200
    11234-MM03-100
    50 µg 
    200 µg 
    100 µg 
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    Reactivity: Human  
    Application: ELISA  
      11234-RP01-400
      11234-RP01-200
      11234-RP01-100
      400 µg 
      200 µg 
      100 µg 
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      Reactivity: Human  
      Application: ELISA  
        11234-T16-50
        11234-T16-200
        11234-T16-100
        50 µg 
        200 µg 
        100 µg 
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        Reactivity: Human  
        Application: ELISA  
          11234-RP02-50
          11234-RP02-200
          11234-RP02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Cynomolgus  
          Application: ELISA  IHC-P  
          • Slide 1
          90162-T24-50
          90162-T24-200
          90162-T24-100
          50 µg 
          200 µg 
          100 µg 
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          REG1A cdna-clone Background

          Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopathy. REG I has been shown to be crucial for induction of ductal epithelial cells to differentiate into some cells. Lithostathine-1-alpha, also known as Pancreatic stone protein, Pancreatic thread protein, Regenerating islet-derived protein 1-alpha, REG1A, REG-1-alpha, and PSPS, is highly expressed in fetal and infant brains. REG1A contains one C-type lectin domain and is a known growth factor affecting pancreatic islet beta cells. REG1A may act as an inhibitor of spontaneous calcium carbonate precipitation. It may also be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. REG1A has been reported to be expressed in human cancers, and it may be positively correlated with patient's prognosis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. High levels of REG1A expression by tumor cells are an independent predictor of a poor prognosis in patients with non-small cell lung cancer (NSCLC).

          Human REG1A cdna-clone References
        • Boonyasrisawat W, et al. (2002) Analysis of the reg1alpha and reg1beta gene transcripts in patients with fibrocalculous pancreatopathy. Southeast Asian J Trop Med Public Health. 33(2): 365-72.
        • Tezel E, et al. (2004) REG I as a marker for human pancreatic acinoductular cells. Hepatogastroenterology. 51(55): 91-6.
        • Geng J, et al. (2009) REG1A predicts recurrence in stage Ta/T1 bladder cancer. Eur J Surg Oncol. 35(8): 852-7.
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