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Rhesus EGFR / HER1 / ErbB1 Protein (His Tag, ECD)

DatasheetReviewsProtocols
Reactivity: Human  
Application: ELISA  IHC-P  IF  IHC-Fr  
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10001-R043-50
10001-R043-100
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: FCM  
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10001-MM08-A-25
10001-MM08-A-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: FCM  
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10001-RE01-A-25
10001-RE01-A-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: FCM  
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10001-MM08-F-25
10001-MM08-F-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: IHC-P  
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10001-MM11-50
10001-MM11-200
10001-MM11-100
50 µg 
200 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  IHC-P  
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10001-T24-50
10001-T24-200
10001-T24-100
50 µg 
200 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: FCM  
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10001-MM08-P-25
10001-MM08-P-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: FCM  IF  ICC/IF  
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10001-MM08-50
10001-MM08-200
10001-MM08-100
50 µg 
200 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: FCM  
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10001-RE01-F-25
10001-RE01-F-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: WB  
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100372-T32-50
100372-T32-200
100372-T32-100
50 µg 
200 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    10001-MM01-50
    10001-MM01-200
    10001-MM01-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10001-RP02-50
      10001-RP02-200
      10001-RP02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: B/N  
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      10001-REN01-500
      10001-REN01-200
      500 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
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      10001-RE01-P-25
      10001-RE01-P-100
      25 Test 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  WB  IF  IP  ICC/IF  
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      10001-R021-50
      10001-R021-100
      10001-R021-1
      50 µg 
      100 µg 
      1 mg 
      Add to Cart
      Reactivity: Human  
      Application: B/N  
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      10001-RE10-500
      10001-RE10-200
      500 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: 
        10001-RE11-50
        10001-RE11-100
        10001-RE11-1
        50 µg 
        100 µg 
        1 mg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10001-RP01-400
          10001-RP01-200
          10001-RP01-100
          400 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  FCM  
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          10001-RE01-50
          10001-RE01-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            51091-R112-50
            51091-R112-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  WB  IP  
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            51091-T52-50
            51091-T52-200
            51091-T52-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  
              51091-R004-50
              51091-R004-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  
                51091-RP01-400
                51091-RP01-200
                51091-RP01-100
                400 µg 
                200 µg 
                100 µg 
                Add to Cart
                Reactivity: Rat  
                Application: ELISA  
                  80100-RP01-200
                  80100-RP01-100
                  200 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Rat  
                  Application: ELISA  WB  IP  
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                  80100-T52-50
                  80100-T52-200
                  80100-T52-100
                  50 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Rhesus  
                  Application: ELISA  
                    90317-T16-50
                    90317-T16-200
                    90317-T16-100
                    50 µg 
                    200 µg 
                    100 µg 
                    Add to Cart
                    Reactivity: Rhesus  
                    Application: ELISA  
                      90317-RP01-400
                      90317-RP01-200
                      90317-RP01-100
                      400 µg 
                      200 µg 
                      100 µg 
                      Add to Cart

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                      EGFR/HER1 protein Background

                      As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.

                      Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

                      Rhesus EGFR/HER1 protein References
                    • Schlessinger, J. (2000) Cell signaling by receptor tyrosine kinases. Cell 103(2): 211-25.
                    • Giaccone, G. (2005) HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy. Ann. Oncol. 16(4): 538-48.
                    • Yarden, Y., et al. (2001) Untangling the ErbB signalling network. Nat. Rev. Mol. Cell. Biol. 2(2): 127-37.
                    • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"