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Influenza A H5N8 (A/breeder duck/Korea/Gochang1/2014 (Gochang1)) Neuraminidase / NA (Codon Optimized) ORF mammalian expression plasmid, N-HA tag

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Description: Active  
Expression host: Human Cells  
    11058-VNAHC-200
    11058-VNAHC-100
    200 U 
    100 U 
    Add to Cart
    Description:   
    Expression host: Baculovirus-Insect Cells  
    • Slide 1
    11058-V07B-50
    11058-V07B-5
    11058-V07B-20
    11058-V07B-10
    50 µg 
    5 µg 
    20 µg 
    10 µg 
    Add to Cart
    Expression host: Human Cells  
    • Slide 1
    40197-V07H-50
    40197-V07H-100
    50 µg 
    100 µg 
    Add to Cart
    Description: Active  
    Expression host: Human Cells  
      11058-VNAHC1-200
      200 U 
      Add to Cart
      Description: Active  
      Expression host: Human Cells  
        11058-VNAHC2-800
        800 U 
        Add to Cart
        Expression host: Human Cells  
          40196-VNAHC-150
          150U 
          Add to Cart
          Description: Active  
          Expression host: Human Cells  
          • Slide 1
          11058-V01H-50
          11058-V01H-100
          11058-V01H-10
          50 µg 
          100 µg 
          10 µg 
          Add to Cart
          Description: Active  
          Expression host: Human Cells  
            40017-VNAHC-800
            800 U 
            Add to Cart
            Description: Active  
            Expression host: Human Cells  
              40017-VNAHC2-80
              40017-VNAHC2-500
              80 U 
              500 U 
              Add to Cart
              Expression host: Human Cells  
              • Slide 1
              40199-V07H-50
              40199-V07H-100
              40199-V07H-10
              50 µg 
              100 µg 
              10 µg 
              Add to Cart
              Description: Active  
              Expression host: Human Cells  
                40017-VNAHC4-1000
                1000 U 
                Add to Cart
                Description: Active  
                Expression host: Human Cells  
                  40017-VNAHC1-600
                  40017-VNAHC1-400
                  600 U 
                  400 U 
                  Add to Cart
                  Expression host: Human Cells  
                  • Slide 1
                  40017-V07H-50
                  40017-V07H-20
                  40017-V07H-10
                  50 µg 
                  20 µg 
                  10 µg 
                  Add to Cart
                  Description: Active  
                  Expression host: Human Cells  
                    40017-VNAHC3-50
                    50 U 
                    Add to Cart
                    Expression host: Human Cells  
                      40235-VNAHC-1500
                      40235-VNAHC-100
                      1500 U 
                      100 U 
                      Add to Cart
                      Description:   
                      Expression host: Baculovirus-Insect Cells  
                      • Slide 1
                      40235-V07B-50
                      40235-V07B-100
                      50 µg 
                      100 µg 
                      Add to Cart
                      Expression host: Human Cells  
                        40045-VNAHC-100
                        100 U 
                        Add to Cart
                        Expression host: Human Cells  
                        • Slide 1
                        40064-V07H-B-50
                        40064-V07H-B-100
                        40064-V07H-B-10
                        50 µg 
                        100 µg 
                        10 µg 
                        Add to Cart
                        Description: Active  
                        Expression host: Human Cells  
                          11676-VNAHC-800
                          11676-VNAHC-60
                          800 U 
                          60 U 
                          Add to Cart
                          Description:   
                          Expression host: Human Cells  
                          • Slide 1
                          40018-V07H-50
                          40018-V07H-20
                          40018-V07H-10
                          50 µg 
                          20 µg 
                          10 µg 
                          Add to Cart
                          Description: Active  
                          Expression host: Human Cells  
                            11676-VNAHC1-60
                            11676-VNAHC1-300
                            60 U 
                            300 U 
                            Add to Cart
                            Expression host: Human Cells  
                            • Slide 1
                            40064-V07H-50
                            40064-V07H-100
                            40064-V07H-10
                            50 µg 
                            100 µg 
                            10 µg 
                            Add to Cart
                            Expression host: Human Cells  
                            • Slide 1
                            40202-V07H-50
                            40202-V07H-100
                            50 µg 
                            100 µg 
                            Add to Cart
                            Expression host: Human Cells  
                              40202-VNAHC-1000
                              40202-VNAHC-100
                              1000 U 
                              100 U 
                              Add to Cart
                              Description: Active  
                              Expression host: Human Cells  
                                40109-VNAHC-20
                                20 U 
                                Add to Cart
                                Expression host: Human Cells  
                                • Slide 1
                                40109-V07H-50
                                40109-V07H-100
                                40109-V07H-10
                                50 µg 
                                100 µg 
                                10 µg 
                                Add to Cart
                                Description: Active  
                                Expression host: Human Cells  
                                  40108-VNAHC-1500
                                  40108-VNAHC-100
                                  1500 U 
                                  100 U 
                                  Add to Cart
                                  Description:   
                                  Expression host: Human Cells  
                                  • Slide 1
                                  40108-V07H-50
                                  40108-V07H-100
                                  40108-V07H-10
                                  50 µg 
                                  100 µg 
                                  10 µg 
                                  Add to Cart
                                  Expression host: Human Cells  
                                  • Slide 1
                                  40034-V07H-50
                                  40034-V07H-100
                                  40034-V07H-10
                                  50 µg 
                                  100 µg 
                                  10 µg 
                                  Add to Cart
                                  Description: Active  
                                  Expression host: Human Cells  
                                    40034-VNAHC-60
                                    40034-VNAHC-500
                                    60 U 
                                    500 U 
                                    Add to Cart
                                    Expression host: Human Cells  
                                    • Slide 1
                                    40040-V07H-50
                                    40040-V07H-100
                                    50 µg 
                                    100 µg 
                                    Add to Cart
                                    Expression host: Baculovirus-Insect Cells  
                                    • Slide 1
                                    40352-V07B-50
                                    40352-V07B-100
                                    50 µg 
                                    100 µg 
                                    Add to Cart
                                    Reactivity: C.perfringens  
                                    Application: ELISA  WB  FCM  
                                      11680-RP02-50
                                      11680-RP02-200
                                      11680-RP02-100
                                      50 µg 
                                      200 µg 
                                      100 µg 
                                      Add to Cart
                                      Reactivity: C.perfringens  
                                      Application: ELISA  WB  
                                        11680-RP01-400
                                        11680-RP01-200
                                        11680-RP01-100
                                        400 µg 
                                        200 µg 
                                        100 µg 
                                        Add to Cart
                                        Reactivity: C.perfringens  
                                        Application: ELISA  IF  ICC/IF  
                                          11680-R112-50
                                          11680-R112-100
                                          50 µg 
                                          100 µg 
                                          Add to Cart
                                          Reactivity: C.perfringens  
                                          Application: ELISA  WB  IP  
                                            11680-MM04-50
                                            11680-MM04-200
                                            11680-MM04-100
                                            50 µg 
                                            200 µg 
                                            100 µg 
                                            Add to Cart
                                            Reactivity: H3N2  
                                            Application: ELISA  IHC-P  FCM  IF  IP  ICC/IF  
                                              40017-RP01-200
                                              40017-RP01-100
                                              200 µg 
                                              100 µg 
                                              Add to Cart
                                              Reactivity: H3N2  
                                              Application: ELISA  WB  IHC-P  IP  
                                              • Slide 1
                                              40017-T60-50
                                              40017-T60-100
                                              50 µg 
                                              100 µg 
                                              Add to Cart
                                              Reactivity: H4N6  
                                              Application: ELISA  IHC-P  FCM  IF  IP  ICC/IF  
                                                40235-RP01-200
                                                40235-RP01-100
                                                200 µg 
                                                100 µg 
                                                Add to Cart
                                                Reactivity: H4N6  
                                                Application: ELISA  WB  IHC-P  IP  
                                                • Slide 1
                                                40235-T60-50
                                                40235-T60-100
                                                50 µg 
                                                100 µg 
                                                Add to Cart
                                                Reactivity: H7N7  
                                                Application: ELISA  WB  IHC-P  IP  
                                                • Slide 1
                                                40202-T60-50
                                                40202-T60-100
                                                50 µg 
                                                100 µg 
                                                Add to Cart
                                                Reactivity: H7N7  
                                                Application: ELISA  IHC-P  FCM  IF  IP  ICC/IF  
                                                  40202-RP01-200
                                                  40202-RP01-100
                                                  200 µg 
                                                  100 µg 
                                                  Add to Cart
                                                  Reactivity: H9N2  
                                                  Application: ELISA  IHC-P  FCM  IF  IP  ICC/IF  
                                                    40040-RP01-200
                                                    40040-RP01-100
                                                    200 µg 
                                                    100 µg 
                                                    Add to Cart
                                                    Reactivity: H9N2  
                                                    Application: ELISA  FCM  IF  ICC/IF  
                                                      40040-MM02-50
                                                      40040-MM02-100
                                                      50 µg 
                                                      100 µg 
                                                      Add to Cart
                                                      Reactivity: H9N2  
                                                      Application: ELISA  WB  
                                                      • Slide 1
                                                      40040-T48-50
                                                      40040-T48-100
                                                      50 µg 
                                                      100 µg 
                                                      Add to Cart
                                                      Reactivity: Influenza  
                                                      Application: ELISA  WB  FCM  IP  
                                                        11058-R001-50
                                                        11058-R001-100
                                                        50 µg 
                                                        100 µg 
                                                        Add to Cart
                                                        Reactivity: Influenza  
                                                        Application: ELISA  WB  IP  
                                                          11058-MM07-50
                                                          11058-MM07-100
                                                          50 µg 
                                                          100 µg 
                                                          Add to Cart

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                                                          Neuraminidase cdna-clone Background

                                                          Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell.

                                                          Influenza neuraminidase is composed of four identical subunits arranged in a square. It is normally attached to the virus surface through a long protein stalk. The active sites are in a deep depression on the upper surface. They bind to polysaccharide chains and clip off the sugars at the end. The surface of neuraminidase is decorated with several polysaccharide chains that are similar to the polysaccharide chains that decorate our own cell surface proteins.

                                                          Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

                                                          Influenza antibody and influenza antibodies are very important research tools for influenza diagnosis, influenza vaccine development, and anti-influenza virus therapy development. Monoclonal or polyclonal antibody can be raised with protein based antigen or peptide based antigen. Antibody raised with protein based antigen could have better specificity and/or binding affinity than antibody raised with peptide based antigen, but cost associated with the recombinant protein antigen is usually higher. Anti influenza virus hemagglutinin (HA) monoclonal antibody or polyclonal antibody can be used for ELISA assay, western blotting detection, Immunohistochemistry (IHC), flow cytometry, neutralization assay, hemagglutinin inhibition assay, and early diagnosis of influenza viral infection.

                                                          Sino Biological has developed state-of-the-art monoclonal antibody development technology platforms: mouse monoclonal antibody and rabbit monoclonal antibody. Our rabbit monoclonal antibody platform is one of a kind and offers some unique advantages over mouse monoclonal antibodies, such as high affinity, low cross-reactivity with rabbit polyclonal antibodies.

                                                          H5N8 Neuraminidase cdna-clone References
                                                        • Sardet C., et al.,(1989), Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter. Cell 56:271-280.
                                                        • Sardet C., et al., (1990), Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kD.Science 247:723-726.
                                                        • Tse C.-M., et al.,(1991), Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger.EMBO J. 10:1957-1967.
                                                        • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"