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TNFR1 / CD120a / TNFRSF1A Antibody, Rabbit PAb

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Description: Active  
Expression host: Human Cells  
  • Slide 1
10872-H03H-50
10872-H03H-100
50 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
10872-H08H-50
10872-H08H-100
50 µg 
100 µg 
Add to Cart
Expression host: Human Cells  
  • Slide 1
50496-M02H-50
50496-M02H-100
50 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
50496-M08H-50
50496-M08H-100
50 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
80181-R08H-5
80181-R08H-20
80181-R08H-100
5 µg 
20 µg 
100 µg 
Add to Cart
Expression host: Human Cells  
  • Slide 1
80181-R02H-50
80181-R02H-100
50 µg 
100 µg 
Add to Cart

TNFR1/TNFRSF1A/CD120a ELISA Pair Set

Detection Limit: 7.81 pg/ml
SEK10872-5
SEK10872-15
5 Plates 
15 Plates 
Add to Cart
Detection Limit: 7.8 pg/ml
SEK50496-5
SEK50496-15
5 Plates 
15 Plates 
Add to Cart

TNFR1/TNFRSF1A/CD120a AntibodyRelated Products

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TNFR1/TNFRSF1A/CD120a antibody Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.

Mouse TNFR1/TNFRSF1A/CD120a antibody References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"