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Mouse SDF-2/SDF2 Gene ORF cDNA clone expression plasmid, C-His tag

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Expression host: Baculovirus-Insect Cells  
  • Slide 1
10950-H08B-20
10950-H08B-10
20 µg 
10 µg 
Add to Cart
Expression host: Baculovirus-Insect Cells  
  • Slide 1
50241-M08B-20
50241-M08B-100
20 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: 
    10950-T16-50
    10950-T16-200
    10950-T16-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Mouse  
    Application: ELISA  WB  IHC-P  IP  
    • Slide 1
    • Slide 1
    • Slide 1
    50241-T60-50
    50241-T60-200
    50241-T60-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart

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    SDF-2/SDF2 cdna-clone Background

    Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from the mouse stromal cell line ST2 as a secretory protein. The amino acid sequence deduced from the murine clone and the human homolog are conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those of yeast dolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.

    Mouse SDF-2/SDF2 cdna-clone References
  • Hamada,T.etal.,1996,Gene.176(1-2):211-214.
  • Anjard,C.etal.,1998,Development.125(20):4067-4075.
  • Kang,H.etal.,2009,Int J Oncol.35(1):205-211. 
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