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Human Coronavirus spike glycoprotein partial ORF mammalian expression plasmid (Codon Optimized)

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Description: Active  
Expression host: Human Cells  
  • Slide 1
40021-V08H-50
40021-V08H-5
40021-V08H-20
40021-V08H-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Expression host: Baculovirus-Insect cells  
  • Slide 1
40150-V08B1-50
40150-V08B1-5
40150-V08B1-20
40150-V08B1-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Expression host: Baculovirus-Insect cells  
  • Slide 1
40150-V31B2-50
40150-V31B2-5
40150-V31B2-20
40150-V31B2-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Expression host: Baculovirus-Insect cells  
  • Slide 1
40150-V08B2-50
40150-V08B2-5
40150-V08B2-20
40150-V08B2-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description:   
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40070-V08B-50
40070-V08B-5
40070-V08B-20
40070-V08B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
40069-V08H-50
40069-V08H-5
40069-V08H-20
40069-V08H-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40069-V08B-50
40069-V08B-5
40069-V08B-20
40069-V08B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40071-V31B-50
40071-V31B-5
40071-V31B-20
40071-V31B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description:   
Expression host: Baculovirus-Insect cells  
  • Slide 1
40071-V31B1-50
40071-V31B1-5
40071-V31B1-20
40071-V31B1-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40069-V08B1-50
40069-V08B1-5
40069-V08B1-20
40069-V08B1-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40071-V05B-50
40071-V05B-5
40071-V05B-20
40071-V05B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description:   
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40071-V08B1-50
40071-V08B1-5
40071-V08B1-20
40071-V08B1-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Reactivity: HCoV  
Application: ELISA  WB  IHC-P  IP  
  • Slide 1
40021-T60-50
40021-T60-100
50 µg 
100 µg 
Add to Cart
Reactivity: HCoV  
Application: ELISA  IHC-P  FCM  IF  IP  ICC/IF  
    40021-RP01-200
    40021-RP01-100
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: HCoV  
    Application: ELISA  FCM  IF  ICC/IF  
      40021-MM07-50
      40021-MM07-100
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: HCoV  
      Application: ELISA  IHC-P  FCM  IF  ICC/IF  
        40021-R028-50
        40021-R028-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: SARS  
        Application: ELISA  WB  FCM  IP  
        • Slide 1
        40150-T52-50
        40150-T52-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: SARS  
        Application: ELISA  IHC-P  FCM  IF  IP  ICC/IF  
          40150-RP01-200
          40150-RP01-100
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: SARS  
          Application: ELISA  WB  IHC-P  IP  
          • Slide 1
          40150-T60-50
          40150-T60-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: SARS  
          Application: ELISA  FCM  IF  ICC/IF  
            40150-MM02-50
            40150-MM02-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: MERS-CoV  
            Application: ELISA  FCM  IF  IP  ICC/IF  
              40069-RP01-200
              40069-RP01-100
              200 µg 
              100 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: WB  IHC  IF  IP  
              • Slide 1
              100210-RP02-50
              100210-RP02-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: ELISA  WB  IHC-P  IP  
              • Slide 1
              40070-T60-50
              40070-T60-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: ELISA  WB  IHC-P  FCM  IHC  IF  IP  ICC/IF  
              • Slide 1
              40069-RP02-50
              40069-RP02-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: ELISA  WB  IHC  IF  IP  
              • Slide 1
              • Slide 1
              100209-RP02-50
              100209-RP02-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: ELISA  WB  IF  IP  
              • Slide 1
              • Slide 1
              100207-RP02-50
              100207-RP02-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: ELISA  WB  IP  
              • Slide 1
              40069-T52-50
              40069-T52-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: MN  
              • Slide 1
              40069-R723-500
              40069-R723-200
              500 µg 
              200 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: ELISA  WB  
              • Slide 1
              40069-T48-50
              40069-T48-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: MERS-CoV  
              Application: ELISA  FCM  IF  ICC/IF  
                40069-MM23-50
                40069-MM23-100
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: MERS-CoV  
                Application: ELISA  WB  IHC  IF  IP  
                • Slide 1
                • Slide 1
                100208-RP02-50
                100208-RP02-100
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: MERS-CoV  
                Application: ELISA  FCM  IF  ICC/IF  
                  40070-MM02-50
                  40070-MM02-100
                  50 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: MERS-CoV  
                  Application: 
                  • Slide 1
                  • Slide 1
                  40070-MM11-50
                  40070-MM11-100
                  50 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: MERS-CoV  
                  Application: WB  IHC-P  IP  
                  • Slide 1
                  40069-T44-50
                  40069-T44-100
                  50 µg 
                  100 µg 
                  Add to Cart
                  40070-V08BL-300 
                  40069-V08BL-300 
                  40071-V05BL-300 
                  40069-V08HL-300 
                  40071-V08B1L-300 
                  40069-V08B1L-300 
                  40071-V31B1L-300 
                  40071-V31BL-300 

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                  CoV Spike glycoprotein cdna-clone Background

                  The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. 

                  HCoV CoV Spike glycoprotein cdna-clone References
                • Shen S, et al. (2007) Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS CoV. Methods Mol Biol. 379: 127-35.
                • Du L, et al. (2009) The spike protein of SARS-CoV--a target for vaccine and therapeutic development. Nat Rev Microbiol. 7 (3): 226-36.
                • Xiao X, et al. (2004) The SARS-CoV S glycoprotein. Cell Mol Life Sci. 61 (19-20): 2428-30.
                • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"