IL3 (Protein | Antibody | cDNA Clone | ELISA Kit)

All IL3 reagents are produced in house and quality controlled, including 15 IL3 Antibody, 2 IL3 ELISA, 9 IL3 Gene, 4 IL3 Lysate, 5 IL3 Protein, 1 IL3 qPCR. All IL3 reagents are ready to use.

IL3 Protein (5)

    IL3 Antibody (15)

      IL3 ELISA Kit & Match Antibody ELISA Pair Set (2)

      IL3 cDNA Clone (9)

      BC069472

      In lentiviral vector

      IL3 qPCR Primer (1)

      IL3 Lysate (4)

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        IL3 Background

        IL3 (interleukin 3), also known as IL-3, is a potent growth promoting cytokine which belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

        IL3 References

        • Meyer CG, et al.. (2011) IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks. Hum Mol Genet. 20(6):1173-81.
        • Zambrano A, et al. (2010) IL-3 controls tau modifications and protects cortical neurons from neurodegeneration. Curr Alzheimer Res. 7(7):615-24.
        • Dentelli P, et al.. (2011) IL-3 is a novel target to interfere with tumor vasculature. Oncogene. 30(50):4930-40.

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