FGF2 Protein, Mouse, Recombinant (His Tag) Product Information
> 95 % as determined by SDS-PAGE.
Please contact us for more information.
Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts.
The ED50 for this effect is typically 0.1-0.6 ng/mL.
A DNA sequence encoding the mouse Fgf2 (NP_032032.1) (Ala11-Ser154) was expressed with a polyhistidine tag at the N-terminus.
The recombinant mouse Fgf2 consists 162 amino acids and predicts a molecular mass of 18.5 kDa.
Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us
for any concerns or special requirements.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -70℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
FGF2 Protein, Mouse, Recombinant (His Tag) in SDS-PAGE
FGF2 Protein, Mouse, Recombinant (His Tag) Alternative Names
bFGF Protein, Mouse;Fgf-2 Protein, Mouse;Fgfb Protein, Mouse
FGF2 Background Information
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.
bFGF/FGF2 Protein & Antibody Products
fibroblast growth factor 2 (basic)
Takayama S,et al. (2001) Periodontal regeneration by FGF-2 (bFGF) in primate models. J Dent Res. 80(12): 2075-9.Niu YJ, et al. (2004) Therapeutic effect of bFGF on retina ischemia-reperfusion injury. Chin Med J (Engl). 117(2): 252-7.Zhang Y,et al. (2004) Expression of aFGF, bFGF, and FGFR1 in ovarian epithelial neoplasm. Chin Med J (Engl). 117(4): 601-3.