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B7 Family Protein

B7 Family Proteins Partial List by Molecule

B7 family protein   B7 family receptor
 

B7 Family Protein by species

B7 Family Protein by Signaling Pathways

Part of Featured B7 Family Proteins

Catalogue Product name Purity Endotoxin
13482-H02H Human B7-H5 / Gi24 / VISTA Protein (ECD, Fc Tag) > 95 % as determined by SDS-PAGE < 1.0 EU/μg protein
10084-H02H Human PD-L1 / B7-H1 / CD274 Protein (Fc Tag) > 95 % as determined by SDS-PAGE < 1.0 EU/μg protein
11188-H08H Human B7-H3 / CD276 Protein (His Tag) > 98 % as determined by SDS-PAGE < 1.0 EU/μg protein
11524-H02H Human CD28 Protein (Fc Tag) > 90 % as determined by SDS-PAGE < 1.0 EU/μg protein
10698-H08H Human CD80 / B7-1 Protein (His Tag) > 95 % as determined by SDS-PAGE < 1.0 EU/μg protein
80381-R02H Rat ICOS / AILIM / CD278 Protein (Fc Tag) > 95 % as determined by SDS-PAGE < 1.0 EU/μg protein
10738-H08H Human B7-H4 / B7S1 / B7x Protein (His Tag) > 95 % as determined by SDS-PAGE < 1.0 EU/μg protein
50017-MCCH Mouse B7-H4 / B7S1 / B7x / VTCN1 Protein > 90 % as determined by SDS-PAGE < 1.0 EU/μg protein
50124-M08H Mouse PD1 / PDCD1 Protein (His Tag) > 95 % as determined by SDS-PAGE < 1.0 EU/μg protein
50466-M02H Mouse ICOS / AILIM / CD278 Protein (Fc Tag) > 97 % as determined by SDS-PAGE < 1.0 EU/μg protein
50503-M02H Mouse CTLA4 / CD152 Protein (Fc Tag) > 95 % as determined by SDS-PAGE < 1.0 EU/μg protein
50446-M02H Mouse CD80 / B7-1 Protein (Fc Tag) > 90 % as determined by SDS-PAGE < 1.0 EU/μg protein

B7 Family Products in Sino Biological Inc.

Background of B7 family protein

The B7 family, belonging to surface glycoproteins, contains immunoglobulin-like domains. B7 family consists of ten known members, which are B7.1 (CD80), B7.2 (CD86), B7-DC (PD-L2), B7-H1 (PD-L1), B7-H2 (ICOSLG), B7-H3 (CD276), B7-H4 (VTCN1), B7-H5 (VISTA), B7-H6 (NCR3LG1) and B7-H7 (HHLA2). The last three members are recently identified. B7 family molecules have the co-stimulation or co-inhibition capability. B7 family members bind to the CD28 family members primarily, such as CD28, CTLA-4, PD-1 and ICOS. B7-H1 has two co-inhibition receptors and B7-H2 has two co-stimulation receptors. The receptors of B7-H3 and B7-H4 have not been identified. B7 family members play important role in maintaining self-tolerance and regulating innate and adaptive immunity in tumor hosts. As an important immunotherapeutic method, B7 family is being studied for the treatment of cancer in humans currently.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"