An anti-idiotype antibody (anti-ID Ab) is able to recognize and bind to the idiotype of another antibody. Sino Biological Inc. has various solutions to problems that you may encounter during the development of anti-idiotype antibodies. We can offer a full range of services - from antigen preparation, anti-idiotypic antibody development to detection method establishment and kit development. Anti-idiotype antibodies are widely used in therapeutic drugs studies: • Antibody drug immunogenicity studies • Vaccine development • Anti-drug antibodies (ADA) for clinical development • Antibody drug pharmacokinetic/pharmacodynamics (PK/PD) studies: detecting free, total or bound drug in blood |
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Type | Not paratope-specific | Paratope-specific | Drug-target complex specific |
Application | Not inhibitory; detects total drug | Inhibitory; detects free drug | Not inhibitory; detects bound drug |
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Service name | Timeline | Deliverables | Pricing |
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Anti-idiotype Rabbit pAb Production Service | 3-4 months | • 0.5mL pre & post immunization serum per rabbit • Purified antibody • CoA |
Please fill in the form and send it to cro-service@sinobiological.com |
Anti-idiotype Mouse mAb Production Service | 4-6 months | • 5 mL positive hybridoma supernatants • Hybridoma cell lines • Purified antibody • CoA • Anti-ID pair screening (Optional) |
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Anti-idiotype Rabbit mAb Production Service | 4-6 months | • Purified antibody • Antibody HC and LC sequence • Vectors containing the HC and LC gene • CoA • Anti-ID pair screening (Optional) |