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acnB Antibody, Rabbit MAb

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    E. coli acnB Antibody Product Information
    Immunogen:Recombinant E. coli acnB protein (Catalog#13102-ENAE)
    Clone ID:102
    Ig Type:Rabbit IgG
    Concentration:
    Endotoxin:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant E. coli acnB (rE. coli acnB; Catalog#13102-ENAE; P36683; Met 1-Val 865).
    Other acnB Antibody Products
    Reactivity: E. coli  
    Application: ELISA  WB  
      13102-MM05-50
      13102-MM05-200
      13102-MM05-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: E. coli  
      Application: ELISA  
        13102-RP02-50
        13102-RP02-200
        13102-RP02-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        Reactivity: E. coli  
        Application: ELISA  WB  
          13102-RP01-400
          13102-RP01-200
          13102-RP01-100
          400 µg 
          200 µg 
          100 µg 
          Add to Cart
          acnB Background

          Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to SoxRS-mediated activation, whereas acnB encodes the major aconitase that is synthesized earlier in the growth cycle than AcnA. It is concluded that AcnB is the major citric acid cycle enzyme. Aconitate hydratase 2 (acnB) catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate, thus it functions as the major citric-acid-cycle enzyme during exponential growth. Escherichia coli acnB serves as either an enzymic catalyst or a mRNA-binding post-transcriptional regulator, depending on the status of its iron sulfur cluster. AcnB represents a large, distinct group of Gram-negative bacterial aconitases that have an altered domain organization relative to mitochondrial aconitase and other aconitases.

          E. coli acnB References
        • Bradbury AJ. et al., 1996, 142 (Pt 2): 389-400.
        • Cunningham L. et al., 1997, Microbiology. 143 (Pt 12): 3795-805.
        • Jordan PA. et al., 1999, Biochem J. 344 Pt 3: 739-46.
        • Williams CH. et al., 2002, Nat Struct Biol. 9(6): 447-52.
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          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"