aFGF Protein & Antibody

acidic Fibroblast Growth Factor

aFGF Protein & Antibody

aFGF, also known as FGF-1, is a member of the fibroblast growth factor family. Sino Biological offers a comprehensive set of tools for FGF related research. These include recombinant proteins (high purity, human cell-expressed), antibodies, ELISA kits, and ORF clones. Our antibody products were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

aFGF Protein, Recombinant

Molecule	Species	Description	Cat. No
aFGF	Human	aFGF protein, Recombinant	10013-HNAE
aFGF	Mouse	aFGF protein, Recombinant	50179-MNAE

  10013-HNAE:  ED₅₀ = 50 - 200 pg / ml. Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts.

  50179-MNAE:  The ED₅₀ for this effect is typically 0.034 ng/mL in the presence of 10 µg/mL heparin. Measured in a cell proliferation assay using NR6R3T3 mouse fibroblasts.

aFGF Antibody

Molecule	Application	Description	Cat. No
Human aFGF	WB, ELISA	Mouse Monoclonal Antibody	10013-MM01
Human aFGF	WB, ELISA	Rabbit Polyclonal Antibody	10013-RP02
Human aFGF	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10013-RP03
Mouse aFGF	WB, ELISA	Rabbit Polyclonal Antibody	50179-RP01
Mouse aFGF	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	50179-RP02

aFGF Related Areas

Neuroscience>>Axon Guidance>>FGF & Receptor>>aFGF

Cancer>>Cancer Biomarkers>>aFGF

Cancer>>Growth Factor & Receptor>>FGF & Receptor>>aFGF

aFGF Alternative Names

AFGF, ECGF, ECGFA, ECGF-beta, ECGFB, FGF-1, FGF1, FGFA, FGF-alpha, GLIO703, HBGF1

aFGF Related Products

Protein Products

Molecule	Species	Description
FGF2/bFGF	Human	bFGF Protein, Recombinant
FGF9	Human	FGF9/Fc Protein, Recombinant
FGF10	Human	FGF10 Protein, Recombinant
FGF18	Mouse	FGF18 Protein, Recombinant
FGF21	Human	FGF21 Protein, Recombinant
FGF21	Mouse	FGF21 Protein, Recombinant
FGFR1/CD331	Human	FGFR1 Protein, Recombinant
FGFR1/CD331	Human	FGFR1/Fc Protein, Recombinant
FGFR1/CD331	Mosue	FGFR1/Fc Protein, Recombinant
FGFR1/CD331	Mosue	FGFR1 Protein, Recombinant
FGFR2/CD332	Human	FGFR2/CD332/Fc Protein, Recombinant
FGFR2/CD332	Human	FGFR2/CD332 Protein, Recombinant
FGFR3/CD334	Mouse	FGFR3/Fc Protein, Recombinant
FGFR4/CD334	Human	FGFR4/Fc Protein, Recombinant
FGFR4/CD334	Human	FGFR4/Fc Protein, Recombinant
FGFR4/CD334	Human	FGFR4/CD334 Protien, Recombinant
FGFR4/CD334	Mouse	FGFR4 Protein, Recombinant
FGFR4/CD334	Mouse	FGFR4/Fc Protein, Recombinant
FGFRL1/FGFR5	Mouse	FGFRL1/FGFR5 Protein, Recombinant

Antibody Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human bFGF/FGF2	WB, ELISA	Rabbit Monoclonal Antibody
Human bFGF/FGF2	ELISA	Rabbit Polyclonal Antibody
Human bFGF/FGF2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human FGFR2	WB, ELISA	FGFR2/CD332 Antibody, Rabbit MAb
Human FGFR2	WB, ELISA	Rabbit Polyclonal Antibody
Human FGFR2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse FGFR4	ELISA	Rabbit Polyclonal Antibody
Mouse FGFR4	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse FGFRL1/FGFR5	WB, ELISA	Rabbit Polyclonal Antibody
Mouse FGFRL1/FGFR5	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
aFGF	Mouse	Mus musculus aFGF cDNA Clone
FGF2/bFGF	Human	Homo sapiens bFGF cDNA Clone(NM_002006.4)
FGF2/bFGF	Mouse	Mus musculus bFGF/FGF2 cDNA Clone
FGF5	Human	Homo sapiens FGF5 transcript variant 1 cDNA Clone(NM_004464.3)
FGF5	Mouse	Mus musculus FGF5 cDNA Clone
FGF7	Human	Homo sapiens FGF7/KGF cDNA Clone (NM_002009.2)
FGF7	Mouse	Mus musculus FGF7/KGF cDNA Clone
FGF9	Human	Homo sapiens FGF9 cDNA Clone(NM_002010.1)
FGF9	Mouse	Mus musculus FGF9 cDNA Clone
FGF10	Human	Homo sapiens FGF10 cDNA Clone(NM_004465.1)
FGF10	Mouse	Mus musculus FGF10 cDNA Clone
FGF11	Mouse	Mus musculus FGF11 cDNA Clone
FGF12	Human	Homo sapiens FGF12 transcript variant 2 cDNA Clone(NM_004113.4)
FGF13	Human	Homo sapiens FGF13 cDNA Clone(NM_004114.2)
FGF13	Mouse	Mus musculus FGF13 cDNA Clone
FGF14	Human	Homo sapiens FGF14 cDNA Clone(NM_004115.3)
FGF14	Mouse	Mus musculus FGF14 cDNA Clone
FGF16	Mouse	Mus musculus FGF16 cDNA Clone
FGF18	Mouse	Mus musculus FGF18 cDNA Clone
FGF21	Human	Homo sapiens FGF21 cDNA Clone(NM_019113.2)
FGF21	Mouse	Mus musculus FGF21 cDNA Clone
FGFR1/CD331	Human	Homo sapiens FGFR1/CD331 cDNA Clone
FGFR1	Mouse	Mus musculus FGFR1 cDNA Clone
FGFR2/CD332	Human	Homo sapiens FGFR2/CD332 cDNA Clone
FGFR3	Mouse	Mus musculus FGFR3 cDNA Clone
FGFR4/CD334	Human	Homo sapiens FGFR4/CD334 cDNA Clone(NM_002011.3)
FGFR4	Mouse	Mus musculus FGFR4 cDNA Clone
FGFRL1/FGFR5	Mouse	Mus musculus FGFRL1/FGFR5 cDNA Clone

aFGF Background

aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.

References

1. Sugiura K, et al. (2007) Co-expression of aFGF and FGFR-1 is predictive of a poor prognosis in patients with esophageal squamous cell carcinoma. Oncol Rep. 17(3): 557-64.
2. Kowalewski R, et al. (2009) Evaluation of aFGF/bFGF and FGF signaling pathway in the wall of varicose veins. J Surg Res. 155 (1): 165-72.