Anti-Lymphotactin Antibody (Rabbit Monoclonal antibody) General Information
Reacts with: Mouse
Has cross-reactivity in ELISA with
No cross-reactivity in ELISA with
Recombinant Mouse XCL1 protein (Catalog#50677-M08B)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse XCL1 (rM XCL1; Catalog#50677-M08B; P47993; Met1-Gly114).
Monoclonal Rabbit IgG Clone #003
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Lymphotactin Antibody (Rabbit Monoclonal antibody) Validated Applications
||This antibody will detect Mouse XCL1 in ELISA pair set (Catalog: # SEK50677). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 50677-R002).
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-Lymphotactin Antibody Alternative Names
Anti-AI661682 Antibody;Anti-ATAC Antibody;Anti-Lptn Antibody;Anti-LTN Antibody;Anti-SCM-1 Antibody;Anti-SCM-1a Antibody;Anti-Scyc1 Antibody
Lymphotactin Background Information
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.
Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
chemokine (C motif) ligand 1
Nguyen KD, et al. (2008) XCL1 enhances regulatory activities of CD4+ CD25(high) CD127(low/-) T cells in human allergic asthma. J Immunol. 181 (8): 5386-95. Dong C, et al. (2005) Glycosylated recombinant human XCL1 / lymphotactin exhibits enhanced biologic activity. J Immunol Methods. 302 (1-2): 136-44. Zavala-Flores LM, et al. (2009) Production of biologically active human lymphotactin (XCL1) by Lactococcus lactis. Biotechnol Lett. 31 (2): 215-20. Guzzo C, Fox JC, Miao H, Volkman BF, Lusso P. Structural Determinants for the Selective Anti-HIV-1 Activity of the All-β Alternative Conformer of XCL1. Kirchhoff F, ed. Journal of Virology. 2015;89(17):9061-9067.