Anti-Lymphotactin Antibody

Cat: 50677-R003
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All Lymphotactin Reagents
Anti-Lymphotactin Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-Lymphotactin Antibody
Validated applications
ELISA,ELISA(Det)
Species reactivity
Reacts with: Mouse
Specificity
Mouse Lymphotactin
Has cross-reactivity in ELISA with Human XCL1
No cross-reactivity in ELISA with Human CXCL1
Immunogen
Recombinant Mouse XCL1 protein (Catalog#50677-M08B)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse XCL1 (rM XCL1; Catalog#50677-M08B; P47993; Met1-Gly114).
Source
Monoclonal Rabbit IgG Clone #003
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Lymphotactin Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
ELISA(Det) 1:1000-1:10000 This antibody will detect Mouse XCL1 in ELISA pair set (Catalog: # SEK50677). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 50677-R002).

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Lymphotactin Antibody Alternative Names
Anti-AI661682 Antibody;Anti-ATAC Antibody;Anti-Lptn Antibody;Anti-LTN Antibody;Anti-SCM-1 Antibody;Anti-SCM-1a Antibody;Anti-Scyc1 Antibody
Lymphotactin Background Information

This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
chemokine (C motif) ligand 1
References
  • Nguyen KD, et al. (2008) XCL1 enhances regulatory activities of CD4+ CD25(high) CD127(low/-) T cells in human allergic asthma. J Immunol. 181 (8): 5386-95.
  • Dong C, et al. (2005) Glycosylated recombinant human XCL1 / lymphotactin exhibits enhanced biologic activity. J Immunol Methods. 302 (1-2): 136-44.
  • Zavala-Flores LM, et al. (2009) Production of biologically active human lymphotactin (XCL1) by Lactococcus lactis. Biotechnol Lett. 31 (2): 215-20.
  • Guzzo C, Fox JC, Miao H, Volkman BF, Lusso P. Structural Determinants for the Selective Anti-HIV-1 Activity of the All-β Alternative Conformer of XCL1. Kirchhoff F, ed. Journal of Virology. 2015;89(17):9061-9067.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Lymphotactin Antibody Rabbit Monoclonal ELISA 90079-R001
    Anti-Lymphotactin Antibody Rabbit Polyclonal ELISA 90079-T16
    Anti-Lymphotactin Antibody Rabbit Polyclonal ELISA 90079-RP01
    Anti-Lymphotactin Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 50677-R002
    Anti-Lymphotactin Antibody Rabbit Polyclonal ELISA 50677-RP01
    Anti-Lymphotactin Antibody Rabbit Polyclonal ELISA 50677-T16
    Anti-Lymphotactin Antibody Rabbit Polyclonal ELISA 10672-T16
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