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> Western Blot Antibody to Rhesus EGF Western Blot Antibody to Rhesus EGF
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Western Blot Antibody to Rhesus EGF Products
All EGF Products list
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Western Blot Antibody to Rhesus EGF
Browse Western Blot Antibody to EGF Products by Following Categories
EGF Protein , Antibody, ELISA Kit, cDNA Clone
Western Blot Antibody to EGF
– Western Blot Antibody to Human EGF
– Western Blot Antibody to Mouse EGF
– Western Blot Antibody to Rat EGF
– Western Blot Antibody to Rhesus EGF
– Western Blot Antibody to Cynomolgus EGF
– Western Blot Antibody to Canine (Dog) EGF
– Western Blot Antibody to Ferret EGF
– Western Blot Antibody to Bovine EGF
Antibody to EGF
Western Blot Antibody to EGF Related Products
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ELISA Antibody to EGF
– ELISA Antibody to Human EGF
– ELISA Antibody to Mouse EGF
– ELISA Antibody to Rat EGF
– ELISA Antibody to Rhesus EGF
– ELISA Antibody to Cynomolgus EGF
– ELISA Antibody to Canine (Dog) EGF
– ELISA Antibody to Ferret EGF
– ELISA Antibody to Bovine EG
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Immunohistochemistry (IHC) Antibody to EGF
– Immunohistochemistry (IHC) Antibody to Human EGF
– Immunohistochemistry (IHC) Antibody to Mouse EGF
– Immunohistochemistry (IHC) Antibody to Rat EGF
– Immunohistochemistry (IHC) Antibody to Rhesus EGF
– Immunohistochemistry (IHC) Antibody to Cynomolgus EGF
– Immunohistochemistry (IHC) Antibody to Canine (Dog) EGF
– Immunohistochemistry (IHC) Antibody to Ferret EGF
– Immunohistochemistry (IHC) Antibody to Bovine EGF
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Flow Cytometry (FACS) Antibody to EGF
– Flow Cytometry (FACS) Antibody to Human EGF
– Flow Cytometry (FACS) Antibody to Mouse EGF
– Flow Cytometry (FACS) Antibody to Rat EGF
– Flow Cytometry (FACS) Antibody to Rhesus EGF
– Flow Cytometry (FACS) Antibody to Cynomolgus EGF
– Flow Cytometry (FACS) Antibody to Canine (Dog) EGF
– Flow Cytometry (FACS) Antibody to Ferret EGF
– Flow Cytometry (FACS) Antibody to Bovine EGF
Browse EGF Antibody by Following Categories
EGF Antibody
– Human EGF Antibody
– Mouse EGF Antibody
– Rat EGF Antibody
– Rhesus EGF Antibody
– Cynomolgus EGF Antibody
– Canine (Dog) EGF Antibody
– Ferret EGF Antibody
– Bovine EGF Antibody
Additional EGF Products
Summary for EGF
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds. As a low-molecular-weight polypeptide, EGF was first purified from the mouse submandibular gland, but since then it was found in many human tissues including submandibular gland, parotid gland. It can also be found in human platelets, macrophages, urine, saliva, milk, and plasma. EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. It results in cellular proliferation, differentiation, and survival. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.
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