Western Blot Antibody to Ferret CD95

Western Blot to Ferret CD95 Products

Sino Biological is the new leader in life science research tool developer worldwide. All our proteins are manufactured in bulk quantities using sequence verified vectors and state-of-the-art mammalian, insect, or E. coli expression processes. All reagents are available in both small retails and bulk packages - both offering 30-80% cost saving compared to currently leading brands. We installed the same quality requirement and assurance for preclinical products to reagent products, hence the quality of Sino Biological products is typically higher than that of other reagent providers.

Browse Western Blot Antibody to CD95 Products by following categories

CD95 Protein , Antibody, ELISA Kit, cDNA Clone

Antibody to CD95

• Western Blot Antibody to CD95

  – Western Blot Antibody to Human CD95

  – Western Blot Antibody to Mouse CD95

  – Western Blot Antibody to Rat CD95

  – Western Blot Antibody to Rhesus CD95

  – Western Blot Antibody to Cynomolgus CD95

  – Western Blot Antibody to Canine (Dog) CD95

  – Western Blot Antibody to Ferret CD95

  – Western Blot Antibody to Bovine CD95

Western Blot Antibody to Ferret CD95 Products

All CD95 Products list

• Western Blot Antibody to CD95

  – Western Blot Antibody to Ferret CD95

Western Blot Antibody to CD95 Related Products

• ELISA Antibody to CD95

  – ELISA Antibody to Human CD95

  – ELISA Antibody to Mouse CD95

  – ELISA Antibody to Rat CD95

  – ELISA Antibody to Rhesus CD95

  – ELISA Antibody to Cynomolgus CD95

  – ELISA Antibody to Canine (Dog) CD95

  – ELISA Antibody to Ferret CD95

  – ELISA Antibody to Bovine CD95

• Immunohistochemistry (IHC) Antibody to CD95

  – Immunohistochemistry (IHC) Antibody to Human CD95

  – Immunohistochemistry (IHC) Antibody to Mouse CD95

  – Immunohistochemistry (IHC) Antibody to Rat CD95

  – Immunohistochemistry (IHC) Antibody to Rhesus CD95

  – Immunohistochemistry (IHC) Antibody to Cynomolgus CD95

  – Immunohistochemistry (IHC) Antibody to Canine (Dog) CD95

  – Immunohistochemistry (IHC) Antibody to Ferret CD95

  – Immunohistochemistry (IHC) Antibody to Bovine CD95

• Flow Cytometry (FACS) Antibody to CD95

  – Flow Cytometry (FACS) Antibody to Human CD95

  – Flow Cytometry (FACS) Antibody to Mouse CD95

  – Flow Cytometry (FACS) Antibody to Rat CD95

  – Flow Cytometry (FACS) Antibody to Rhesus CD95

  – Flow Cytometry (FACS) Antibody to Cynomolgus CD95

  – Flow Cytometry (FACS) Antibody to Canine (Dog) CD95

  – Flow Cytometry (FACS) Antibody to Ferret CD95

  – Flow Cytometry (FACS) Antibody to Bovine CD95

Browse CD95 Antibody by following categories

• CD95 Antibody

  – Human CD95 Antibody

  – Mouse CD95 Antibody

  – Rat CD95 Antibody

  – Rhesus CD95 Antibody

  – Cynomolgus CD95 Antibody

  – Canine (Dog) CD95 Antibody

  – Ferret CD95 Antibody

  – Bovine CD95 Antibody

Additional CD95 Products

• CD95 Protein

• CD95 ELISA Kit

• CD95 cDNA Clone

Summary of Western Blot Antibody to Ferret CD95

CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized by the presence of an 80 amino acid death domain in its cytoplasmic tail. This domain is essential for the recruitment of a number of signaling components upon activation by either agonistic anti-CD95 antibodies or cognate CD95 ligand that initiate apoptosis. The complex of proteins that forms upon triggering of CD95 is called the death-inducting signaling complex (DISC). The DISC consists of an adaptor protein and initiator caspases and is essential for induction of apoptosis. CD95 is also crucial for the negative selection of B cells within the germinal center (GC). Impairment of CD95-mediated apoptosis results in defective affinity maturation and the persistence of autoreactive B-cell clones. Changes in the expression of CD95 and/or its ligand CD95L are frequently found in human cancer. The downregulation or mutation of CD95 has been proposed as a mechanism by which cancer cells avoid destruction by the immune system through reduced apoptosis sensitivity. Thus, CD95 has therefore been viewed as a tumor suppressor. CD95 has been reported to be involved in the activation of NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and the alternate pathways for CTL-mediated cytotoxicity. Accordingly, this protein is implicated in the pathogenesis of various malignancies and diseases of the immune system. The CD95/CD95L system was implicated in the etiology of inflammatory bowel disease (IBD) based, primarily, on the finding that CD95 is highly expressed in the intestinal epithelial cells and that epithelial apoptosis is increased in IBD.

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