VWF / Von Willebrand Factor Protein & Antibody

VWF / Von Willebrand Factor Protein & Antibody

Sino Biological offers a comprehensive set of research tools for Von Willebrand Factor (VWF) related research. These include recombinant proteins, mouse monoclonal antibodies and rabbit polyclonal antibodies. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

VWF / Von Willebrand Factor Protein, Recombinant

Molecule	Species	Description	Cat. No
VWF	Human	VWF Protein, Recombinant	10973-H08C

VWF / Von Willebrand Factor Antibody

Molecule	Application	Description	Cat. No
Human VWF	WB	Mouse Monoclonal Antibody	10973-MM01
Human VWF	ELISA	Mouse Monoclonal Antibody	10973-MM02
Human VWF	WB, ELISA, IHC	Rabbit Monoclonal Antibody	10973-R111
Human VWF	WB, ELISA	Rabbit Polyclonal Antibody	10973-RP03
Human VWF	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10973-RP04

VWF / Von Willebrand Factor Related Areas

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hemangioblast>>Endothelial Cell Marker>>VWF

Immunology>>Innate Immunity>>Coagulation>>VWF

Cardiovascular>>Coagulation>>VWF

Cardiovascular>>Platelet>>VWF

VWF / Von Willebrand Factor Alternative Names

VWF, VWD, F8VWF [Homo sapiens]

Vwf, VWD, 6820430P06Rik, AI551257, B130011O06Rik, C630030D09, F8VWF [Mus musculus]

VWF / Von Willebrand Factor Background

Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.

VWF / Von Willebrand Factor Related Studies

1. Sadler JE. (1998) Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem, 67: 395-424.
2. Batlle J, et al. (2009) Von Willebrand factor/factor VIII concentrates in the treatment of von Willebrand disease. Blood Coagul Fibrinolysis. 20(2):89-100.
3. Sadler JE. (2009) von Willebrand factor assembly and secretion. J Thromb Haemost. 7 Suppl 1:24-7.
4. Auton M, et al. (2010) The mechanism of VWF-mediated platelet GPIbalpha binding. Biophys J. 99(4):1192-201.
5. Bowen DJ. (2010) Sugar targets VWF for the chop. Blood. 115(13):2565.
6. López JA, et al. (2010) VWF self-association: more bands for the buck. Blood. 116(19):3693-4.