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vWF Antibody, Rabbit MAb

  • vWF Antibody, Rabbit MAb, Immunohistochemistry
  • vWF Antibody, Rabbit MAb, Immunohistochemistry
  • vWF Antibody, Rabbit MAb, Immunohistochemistry
  • vWF Antibody, Rabbit MAb, Immunohistochemistry
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Human vWF Antibody Product Information
Immunogen:Recombinant Human vWF protein (Catalog#10973-H08C)
Clone ID:111
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human von Willebrand factor (rh vWF; Catalog#10973-H08C; Met 1-Lys 2813; NP_000543.2) .
Human vWF Antibody IHC Application Image
vWF Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunohistochemical staining of formalin fixed, paraffin-embedded human lymphonode showing blood vessel staining (1 μg/mL).
vWF Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunohistochemical staining of formalin fixed, paraffin-embedded human muscle showing blood vessel staining (1 μg/mL).
vWF Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunohistochemical staining of formalin fixed, paraffin-embedded human stomach showing blood vessel staining (1 μg/mL).
vWF Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunohistochemical staining of formalin fixed, paraffin-embedded human tonsil showing blood vessel staining (1 μg/mL).
Other vWF Antibody Products
Immunochemical staining of human CCNF in human brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
VWF/Von Willebrand Factor Background

Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.

Human VWF/Von Willebrand Factor References
  • Sadler JE. (1998) Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem, 67: 395-424.
  • Batlle J, et al. (2009) Von Willebrand factor/factor VIII concentrates in the treatment of von Willebrand disease. Blood Coagul Fibrinolysis. 20(2):89-100.
  • Sadler JE. (2009) von Willebrand factor assembly and secretion. J Thromb Haemost. 7 Suppl 1:24-7.
  • Auton M, et al. (2010) The mechanism of VWF-mediated platelet GPIbalpha binding. Biophys J. 99(4):1192-201.
  • Bowen DJ. (2010) Sugar targets VWF for the chop. Blood. 115(13):2565.
  • Lpez JA, et al. (2010) VWF self-association: more bands for the buck. Blood. 116(19):3693-4.
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    Catalog: 10973-R111-1
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    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"