|Recombinant Human vWF protein (Catalog#10973-H08C)|
|0.2 μm filtered solution in PBS|
|This antibody was obtained from a rabbit immunized with purified, recombinant Human von Willebrand factor (rh vWF; Catalog#10973-H08C; Met 1-Lys 2813; NP_000543.2) .|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human vWF. The detection limit for Human vWF is approximately 0.0049 ng/well.
ELISA(Det): 0.1-1 µg/ml
This antibody will detect Human VWF / Von Willebrand Factor in ELISA pair set (Catalog: # SEKA10973). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10973-MM05).
IHC-P: 0.5-5 μg/mL
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.