Anti-Vitronectin Antibody

Cat: 50585-RP02

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Anti-Vitronectin Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Vitronectin Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse Vitronectin
Recombinant Mouse Vitronectin / VTN protein (Catalog#50585-M08H)
Produced in rabbits immunized with purified, recombinant Mouse Vitronectin / VTN (rM Vitronectin / VTN; Catalog#50585-M08H; NP_035837.1; Met 1-Lys 478). Vitronectin / VTN specific IgG was purified by Mouse Vitronectin / VTN affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Vitronectin Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
IHC-P 1:500-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Vitronectin Antibody (Rabbit Polyclonal antibody) Images
Mouse Vitronectin/VTN Immunohistochemistry(IHC) 3155
Immunochemical staining of mouse VTN in mouse lungy with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Mouse Vitronectin/VTN Immunohistochemistry(IHC) 3156
Immunochemical staining of mouse VTN in mouse liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
Anti-Vitronectin Antibody Alternative Names
Anti-AI256434 Antibody;Anti-Vn Antibody
Vitronectin Background Information

Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.

Full Name
  • Ekmeki OB, et al. (2006) Vitronectin in atherosclerotic disease. Clin Chim Acta. 368(1-2): 77-83.
  • Derer W, et al. (2009) Vitronectin concentrations predict risk in patients undergoing coronary stenting. Circ Cardiovasc Interv. 2(1): 14-9.
  • Heyman L, et al. (2010) Mesothelial vitronectin stimulates migration of ovarian cancer cells. Cell Biol Int. 34(5): 493-502.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Vitronectin Antibody Rabbit Monoclonal ELISA,IHC-P 50585-R019
    Anti-Vitronectin Antibody Rabbit Polyclonal ELISA 50585-RP01
    Anti-Vitronectin Antibody Rabbit Monoclonal ELISA 10424-R102
    Anti-Vitronectin Antibody Rabbit Monoclonal ELISA 10424-R103
    Anti-Vitronectin Antibody Rabbit Polyclonal WB,ELISA 10424-RP01
    Anti-Vitronectin Antibody Mouse Monoclonal ELISA(Det) 10424-MM03
    Anti-Vitronectin Antibody Mouse Monoclonal ELISA,ELISA(Cap) 10424-MM11
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