VWC2 Matched ELISA Antibody Pair Set,Human

Cat: SEK12071
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All VWC2 Reagents
CRO Services
Product recommended

All VWC2 Reagents
VWC2 Matched ELISA Antibody Pair Set,Human General Information
Product name
VWC2 Matched ELISA Antibody Pair Set,Human
Assay type
Solid Phase Sandwich ELISA
Specificity
Quantitative determination of Human VWC2
Assay range
7.81-500
Materials provided
1. Capture Antibody 0.19 mg/mL of mouse anti-VWC2 monoclonal antibody, Dilute to a working concentration of 2 μg/mL in CBS before coating. (Catalog: # 12071-MM08)
2. Detection Antibody 0.25 mg/mL mouse anti-VWC2 monoclonal antibody conjugated to horseradish-peroxidase (HRP). Dilute to working concentration of 1 μg/mL in detection antibody dilution buffer before use. (Catalog: # 12071-MM03)
3. Standard Each vial contains 12 ng of recombinant VWC2. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve usi ng 2-fold serial dilutions in sample dilution buffer, and a high standard of 500 pg/mL is recommended.
Product overview
This VWC2 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human VWC2 . It contains Human VWC2 capture antibody, Human VWC2 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human VWC2 protein. This Pair Set is at affordable price for researchers.
Shipping
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
Storage
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Protect it from prolonged exposure to light. Aliquot and store at -20℃ to -80℃ and for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.
VWC2 Matched ELISA Antibody Pair Set,Human Images
Human VWC2 ELISA Pair Set Standard Curve 13956
VWC2 Matched ELISA Antibody Pair Set,Human Alternative Names
PSST739 Matched ELISA Antibody Pair Set, Human;UNQ739 Matched ELISA Antibody Pair Set, Human
VWC2 Background Information

Brorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein which contains two VWFC domains. VWC2 / Brorin is a BMP antagonist which may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neural tissues in embryos and also predominantly expressed in the adult brain. In the brain, the expression was detected in neurons, but not glial cells. The neural tissue-specific expression profile of Brorin is quite distinct from that of any other member of the Chordin family. VWC2 / Brorin protein promoted neurogenesis, but not astrogenesis, in mouse neural precursor cells. VWC2 / Brorin is a novel secreted BMP antagonist that potentially plays roles in neural development and functions.

Full Name
von Willebrand factor C domain containing 2
References
  • Koike,N. et al., 2007, J Biol Chem. 282 (21):15843-50.
  • Elis,S. et al., 2009,Mol Reprod Dev. 76 (11):1043-55.
  • Zhang,J.L. et al., 2010,PLoS One. 5 (9):e12846.
  • Product Description Assay Range (pg/ml) Sample Type Catalog# (PDF)
    info info
    添加购物车成功! 添加购物车失败!